The early diagnosis of alzheimer's disease: From behavioral to genetic study

Yanna Ren, Weiping Yang, Xiaoyu Tang, Fengxia Wu, Satoshi Takahashi, Jinglong Wu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Alzheimer's disease, a common form of dementia, is a type of neurodegenerative disease that affects more than 30% of the population older than 85. Clinically, it is characterized as memory loss and cognitive decline. Pathologically, its symptoms include cerebral atrophy, amyloid plaques and NFTs. Generally, the life expectancy is no more than nine years after the definite diagnosis, and life expectancy exceeds 14 years in only 3% of patients. Presently, there is no effective treatment to stop the process; the only measures we can take are to ease or improve symptoms temporarily. Therefore, it is necessary to diagnosis the disease in the early stage, such as through imaging detection via CT, MRI, PET and MSR, or prediction before the disease (genetic examination). However, literature data have supported the notion that Alzheimer's disease patients show cognitive reserve abilities to some degree. In the future, research perspectives may focus on the cognitive training paradigms in compensatory and restorative strategies.

Original languageEnglish
Title of host publicationImproving the Quality of Life for Dementia Patients through Progressive Detection, Treatment, and Care
PublisherIGI Global
Pages1-16
Number of pages16
ISBN (Electronic)9781522509264
ISBN (Print)1522509259, 9781522509257
DOIs
Publication statusPublished - Oct 11 2016

ASJC Scopus subject areas

  • Medicine(all)

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