Abstract
The difference in temporal distribution of c-Fos-immunoreactivity (Fos-IR) was assessed in the medullary dorsal horn (MDH) and in the dorsomedial part of the trigeminal subnucleus oralis (Vodm) following experimental tooth movement of the rat maxillary molars. The number of MDH c-Fos-immunoreactive neurons increased bilaterally at 2 h and decreased markedly by 12 h, and then increased again with a small peak at 48 h. In contrast, Vodm c-Fos expression was not up-regulated until 12 h, but increased in number after 24 h, which increase lasted until 72 h. These findings indicate that experimental tooth movement induced nociceptive c-Fos response in a biphasic manner. Furthermore, the later response appeared after 24 h, and lasted for a few days, mainly manifested in the Vodm during experimental tooth movement. Copyright (C) 2000 Elsevier Science Ireland Ltd.
| Original language | English |
|---|---|
| Pages (from-to) | 205-208 |
| Number of pages | 4 |
| Journal | Neuroscience Letters |
| Volume | 283 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Apr 14 2000 |
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Keywords
- c-Fos
- Medullary dorsal horn
- Nociception
- Subnucleus oralis
- Tooth movement
- Two responses
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
The difference in temporal distribution of c-Fos immunoreactive neurons between the medullary dorsal horn and the trigeminal subnucleus oralis in the rat following experimental tooth movement. / Fujiyoshi, Yoshiaki; Yamashiro, Takashi; Deguchi, Toru; Sugimoto, Tomosada; Takano-Yamamoto, Teruko.
In: Neuroscience Letters, Vol. 283, No. 3, 14.04.2000, p. 205-208.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The difference in temporal distribution of c-Fos immunoreactive neurons between the medullary dorsal horn and the trigeminal subnucleus oralis in the rat following experimental tooth movement
AU - Fujiyoshi, Yoshiaki
AU - Yamashiro, Takashi
AU - Deguchi, Toru
AU - Sugimoto, Tomosada
AU - Takano-Yamamoto, Teruko
PY - 2000/4/14
Y1 - 2000/4/14
N2 - The difference in temporal distribution of c-Fos-immunoreactivity (Fos-IR) was assessed in the medullary dorsal horn (MDH) and in the dorsomedial part of the trigeminal subnucleus oralis (Vodm) following experimental tooth movement of the rat maxillary molars. The number of MDH c-Fos-immunoreactive neurons increased bilaterally at 2 h and decreased markedly by 12 h, and then increased again with a small peak at 48 h. In contrast, Vodm c-Fos expression was not up-regulated until 12 h, but increased in number after 24 h, which increase lasted until 72 h. These findings indicate that experimental tooth movement induced nociceptive c-Fos response in a biphasic manner. Furthermore, the later response appeared after 24 h, and lasted for a few days, mainly manifested in the Vodm during experimental tooth movement. Copyright (C) 2000 Elsevier Science Ireland Ltd.
AB - The difference in temporal distribution of c-Fos-immunoreactivity (Fos-IR) was assessed in the medullary dorsal horn (MDH) and in the dorsomedial part of the trigeminal subnucleus oralis (Vodm) following experimental tooth movement of the rat maxillary molars. The number of MDH c-Fos-immunoreactive neurons increased bilaterally at 2 h and decreased markedly by 12 h, and then increased again with a small peak at 48 h. In contrast, Vodm c-Fos expression was not up-regulated until 12 h, but increased in number after 24 h, which increase lasted until 72 h. These findings indicate that experimental tooth movement induced nociceptive c-Fos response in a biphasic manner. Furthermore, the later response appeared after 24 h, and lasted for a few days, mainly manifested in the Vodm during experimental tooth movement. Copyright (C) 2000 Elsevier Science Ireland Ltd.
KW - c-Fos
KW - Medullary dorsal horn
KW - Nociception
KW - Subnucleus oralis
KW - Tooth movement
KW - Two responses
UR - http://www.scopus.com/inward/record.url?scp=0034646924&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034646924&partnerID=8YFLogxK
U2 - 10.1016/S0304-3940(00)00962-9
DO - 10.1016/S0304-3940(00)00962-9
M3 - Article
C2 - 10754223
AN - SCOPUS:0034646924
VL - 283
SP - 205
EP - 208
JO - Neuroscience Letters
JF - Neuroscience Letters
SN - 0304-3940
IS - 3
ER -