The difference in temporal distribution of c-Fos immunoreactive neurons between the medullary dorsal horn and the trigeminal subnucleus oralis in the rat following experimental tooth movement

Yoshiaki Fujiyoshi, Takashi Yamashiro, Toru Deguchi, Tomosada Sugimoto, Teruko Takano-Yamamoto

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

The difference in temporal distribution of c-Fos-immunoreactivity (Fos-IR) was assessed in the medullary dorsal horn (MDH) and in the dorsomedial part of the trigeminal subnucleus oralis (Vodm) following experimental tooth movement of the rat maxillary molars. The number of MDH c-Fos-immunoreactive neurons increased bilaterally at 2 h and decreased markedly by 12 h, and then increased again with a small peak at 48 h. In contrast, Vodm c-Fos expression was not up-regulated until 12 h, but increased in number after 24 h, which increase lasted until 72 h. These findings indicate that experimental tooth movement induced nociceptive c-Fos response in a biphasic manner. Furthermore, the later response appeared after 24 h, and lasted for a few days, mainly manifested in the Vodm during experimental tooth movement. Copyright (C) 2000 Elsevier Science Ireland Ltd.

Original languageEnglish
Pages (from-to)205-208
Number of pages4
JournalNeuroscience Letters
Volume283
Issue number3
DOIs
Publication statusPublished - Apr 14 2000

Fingerprint

Tooth Movement Techniques
Neurons
Spinal Cord Dorsal Horn

Keywords

  • c-Fos
  • Medullary dorsal horn
  • Nociception
  • Subnucleus oralis
  • Tooth movement
  • Two responses

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The difference in temporal distribution of c-Fos immunoreactive neurons between the medullary dorsal horn and the trigeminal subnucleus oralis in the rat following experimental tooth movement. / Fujiyoshi, Yoshiaki; Yamashiro, Takashi; Deguchi, Toru; Sugimoto, Tomosada; Takano-Yamamoto, Teruko.

In: Neuroscience Letters, Vol. 283, No. 3, 14.04.2000, p. 205-208.

Research output: Contribution to journalArticle

Fujiyoshi, Yoshiaki ; Yamashiro, Takashi ; Deguchi, Toru ; Sugimoto, Tomosada ; Takano-Yamamoto, Teruko. / The difference in temporal distribution of c-Fos immunoreactive neurons between the medullary dorsal horn and the trigeminal subnucleus oralis in the rat following experimental tooth movement. In: Neuroscience Letters. 2000 ; Vol. 283, No. 3. pp. 205-208.
@article{5ba664be510746b99755c60bb7b07965,
title = "The difference in temporal distribution of c-Fos immunoreactive neurons between the medullary dorsal horn and the trigeminal subnucleus oralis in the rat following experimental tooth movement",
abstract = "The difference in temporal distribution of c-Fos-immunoreactivity (Fos-IR) was assessed in the medullary dorsal horn (MDH) and in the dorsomedial part of the trigeminal subnucleus oralis (Vodm) following experimental tooth movement of the rat maxillary molars. The number of MDH c-Fos-immunoreactive neurons increased bilaterally at 2 h and decreased markedly by 12 h, and then increased again with a small peak at 48 h. In contrast, Vodm c-Fos expression was not up-regulated until 12 h, but increased in number after 24 h, which increase lasted until 72 h. These findings indicate that experimental tooth movement induced nociceptive c-Fos response in a biphasic manner. Furthermore, the later response appeared after 24 h, and lasted for a few days, mainly manifested in the Vodm during experimental tooth movement. Copyright (C) 2000 Elsevier Science Ireland Ltd.",
keywords = "c-Fos, Medullary dorsal horn, Nociception, Subnucleus oralis, Tooth movement, Two responses",
author = "Yoshiaki Fujiyoshi and Takashi Yamashiro and Toru Deguchi and Tomosada Sugimoto and Teruko Takano-Yamamoto",
year = "2000",
month = "4",
day = "14",
doi = "10.1016/S0304-3940(00)00962-9",
language = "English",
volume = "283",
pages = "205--208",
journal = "Neuroscience Letters",
issn = "0304-3940",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

TY - JOUR

T1 - The difference in temporal distribution of c-Fos immunoreactive neurons between the medullary dorsal horn and the trigeminal subnucleus oralis in the rat following experimental tooth movement

AU - Fujiyoshi, Yoshiaki

AU - Yamashiro, Takashi

AU - Deguchi, Toru

AU - Sugimoto, Tomosada

AU - Takano-Yamamoto, Teruko

PY - 2000/4/14

Y1 - 2000/4/14

N2 - The difference in temporal distribution of c-Fos-immunoreactivity (Fos-IR) was assessed in the medullary dorsal horn (MDH) and in the dorsomedial part of the trigeminal subnucleus oralis (Vodm) following experimental tooth movement of the rat maxillary molars. The number of MDH c-Fos-immunoreactive neurons increased bilaterally at 2 h and decreased markedly by 12 h, and then increased again with a small peak at 48 h. In contrast, Vodm c-Fos expression was not up-regulated until 12 h, but increased in number after 24 h, which increase lasted until 72 h. These findings indicate that experimental tooth movement induced nociceptive c-Fos response in a biphasic manner. Furthermore, the later response appeared after 24 h, and lasted for a few days, mainly manifested in the Vodm during experimental tooth movement. Copyright (C) 2000 Elsevier Science Ireland Ltd.

AB - The difference in temporal distribution of c-Fos-immunoreactivity (Fos-IR) was assessed in the medullary dorsal horn (MDH) and in the dorsomedial part of the trigeminal subnucleus oralis (Vodm) following experimental tooth movement of the rat maxillary molars. The number of MDH c-Fos-immunoreactive neurons increased bilaterally at 2 h and decreased markedly by 12 h, and then increased again with a small peak at 48 h. In contrast, Vodm c-Fos expression was not up-regulated until 12 h, but increased in number after 24 h, which increase lasted until 72 h. These findings indicate that experimental tooth movement induced nociceptive c-Fos response in a biphasic manner. Furthermore, the later response appeared after 24 h, and lasted for a few days, mainly manifested in the Vodm during experimental tooth movement. Copyright (C) 2000 Elsevier Science Ireland Ltd.

KW - c-Fos

KW - Medullary dorsal horn

KW - Nociception

KW - Subnucleus oralis

KW - Tooth movement

KW - Two responses

UR - http://www.scopus.com/inward/record.url?scp=0034646924&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034646924&partnerID=8YFLogxK

U2 - 10.1016/S0304-3940(00)00962-9

DO - 10.1016/S0304-3940(00)00962-9

M3 - Article

C2 - 10754223

AN - SCOPUS:0034646924

VL - 283

SP - 205

EP - 208

JO - Neuroscience Letters

JF - Neuroscience Letters

SN - 0304-3940

IS - 3

ER -