The clinical outcomes of hemicortical extracorporeal irradiated autologous bone graft after tumor resection of bone and soft tissue sarcoma

Tomoki Nakamura, Tomohiro Fujiwara, Yusuke Tsuda, Adesegun Abudu, Yoshihito Nomoto, Akinori Takada, Yutaka Toyomasu, Tomohito Hagi, Kunihiro Asanuma, Akihiro Sudo

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background/Aim: We analyzed the process of healing at osteotomy sites and timing of achievement of full weight-bearing in sarcoma patients who underwent hemicortical or intercalary reconstruction using the extracorporeal irradiated autologous bone graft technique. Patients and Methods: We studied 10 patients who had undergone tumor resection and reconstruction with hemicortical extracorporeal irradiated autologous bone graft at mid-shaft femur or tibia. The control group consisted of 30 patients who received the reconstruction using intercalary bone graft. Results: Full weight-bearing was achieved in all 10 patients at a median time of 4.8 months. Function was excellent in all patients. When comparing the clinical outcome among the patients who received intercalary and hemicortical grafts, the duration to full weight-bearing achievement in patients who received hemicortical graft was shorter than that in those with intercalary graft. Conclusion: Early full weight-bearing may be achieved in patients undergoing hemicortical resection and reconstruction using extracorporeal irradiated autologous bone graft.

Original languageEnglish
Pages (from-to)5605-5610
Number of pages6
JournalAnticancer research
Volume39
Issue number10
DOIs
Publication statusPublished - 2019
Externally publishedYes

Keywords

  • Autologous bone graft
  • Extracorporeal irradiation
  • Hemicortical
  • Sarcoma
  • Weight-bearing

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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