The clinical application of hydrogen as a medical treatment

Atsuyoshi Iida, Nobuyuki Nosaka, Tetsuya Yumoto, Emily Knaup, Hiromichi Naito, Chihiro Nishiyama, Yasuaki Yamakawa, Kohei Tsukahara, Michihisa Terado, Keiji Sato, Toyomu Ugawa, Atsunori Nkao

Research output: Contribution to journalReview article

12 Citations (Scopus)

Abstract

In recent years, it has become evident that molecular hydrogen is a particularyl effective treatment for various disease models such as ischemia-reperfusion injury; as a result, research on hydrogen has progressed rapidly. Hydrogen has been shown to be effective not only through intake as a gas, but also as a liquid medication taken orally, intravenously, or locally. Hydrogen's effectiveness is thus multifaceted. Herein we review the recent research on hydrogen-rich water, and we examine the possibilities for its clinical application. Now that hydrogen is in the limelight as a gaseous signaling molecule due to its potential ability to inhibit oxidative stress signaling, new research developments are highly anticipated.

Original languageEnglish
Pages (from-to)331-338
Number of pages8
JournalActa Medica Okayama
Volume70
Issue number5
Publication statusPublished - 2016

Fingerprint

Hydrogen
Research
Oxidative stress
Reperfusion Injury
Oxidative Stress
Gases
Molecules
Water
Liquids

Keywords

  • Antioxidant effect
  • Clinical tests
  • Gaseous signaling molecule
  • Hydrogen
  • Medical gas

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Iida, A., Nosaka, N., Yumoto, T., Knaup, E., Naito, H., Nishiyama, C., ... Nkao, A. (2016). The clinical application of hydrogen as a medical treatment. Acta Medica Okayama, 70(5), 331-338.

The clinical application of hydrogen as a medical treatment. / Iida, Atsuyoshi; Nosaka, Nobuyuki; Yumoto, Tetsuya; Knaup, Emily; Naito, Hiromichi; Nishiyama, Chihiro; Yamakawa, Yasuaki; Tsukahara, Kohei; Terado, Michihisa; Sato, Keiji; Ugawa, Toyomu; Nkao, Atsunori.

In: Acta Medica Okayama, Vol. 70, No. 5, 2016, p. 331-338.

Research output: Contribution to journalReview article

Iida, A, Nosaka, N, Yumoto, T, Knaup, E, Naito, H, Nishiyama, C, Yamakawa, Y, Tsukahara, K, Terado, M, Sato, K, Ugawa, T & Nkao, A 2016, 'The clinical application of hydrogen as a medical treatment', Acta Medica Okayama, vol. 70, no. 5, pp. 331-338.
Iida A, Nosaka N, Yumoto T, Knaup E, Naito H, Nishiyama C et al. The clinical application of hydrogen as a medical treatment. Acta Medica Okayama. 2016;70(5):331-338.
Iida, Atsuyoshi ; Nosaka, Nobuyuki ; Yumoto, Tetsuya ; Knaup, Emily ; Naito, Hiromichi ; Nishiyama, Chihiro ; Yamakawa, Yasuaki ; Tsukahara, Kohei ; Terado, Michihisa ; Sato, Keiji ; Ugawa, Toyomu ; Nkao, Atsunori. / The clinical application of hydrogen as a medical treatment. In: Acta Medica Okayama. 2016 ; Vol. 70, No. 5. pp. 331-338.
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