Abstract
In order to speculate the role of platelet in the wound healing, we examined platelet count in 27 patients who showed anastomotic leakage after gastrointestinal surgery. Thirty-nine patients who did not show leakage were served as control. Results were as follows: (1) The maximal values of platelet after surgery correlated with the surgical invasion. (2) Platelet count showed biphasic pattern after surgery. At first platelet count decreased. Then the count increased and reached its maximal values in the 2nd week in the control group. However, the maximal values were obtained in the 3rd week in the case of the patients with leakage. After that, platelet count decreased to normal level in healing stage. This tendency was more prominent in early leakage group than delayed leakage group. (3) The changing pattern of platelet count after surgery did not coincide with that of white cell count. White cell count was normal in 10 out of 27 (37%) in leakage cases. However, the platelet count in these cases increased in 9 out of 10 (90%). Therefore, it is concluded that the maximum of platelet after surgery reflects surgical invasion well. The changing pattern of platelet count after surgery is useful in speculating healing stage and detecting anastomotic leakage early.
| Original language | English |
|---|---|
| Pages (from-to) | 483-487 |
| Number of pages | 5 |
| Journal | Japanese Journal of National Medical Services |
| Volume | 48 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1994 |
| Externally published | Yes |
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Keywords
- anastomotic leakage
- cytokine
- platelet count
- wound healing
ASJC Scopus subject areas
- Medicine(all)
Cite this
The changing pattern of platelet count after gastrointestinal surgery according to the healing stage. / Takeuchi, Hitoshi; Konaga, Eiji; Kuinose, Masahiko; Nishizaki, Masahiko; Murakami, Takayoshi; Kagawa, Shunsuke; Yoshioka, Takashi; Kanaoka, Yuhji; Tanakaya, Kohji; Yasui, Yoshimasa; Tanemoto, Kazuo; Kashitani, Masaaki; Kobayashi, Genso.
In: Japanese Journal of National Medical Services, Vol. 48, No. 7, 1994, p. 483-487.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The changing pattern of platelet count after gastrointestinal surgery according to the healing stage
AU - Takeuchi, Hitoshi
AU - Konaga, Eiji
AU - Kuinose, Masahiko
AU - Nishizaki, Masahiko
AU - Murakami, Takayoshi
AU - Kagawa, Shunsuke
AU - Yoshioka, Takashi
AU - Kanaoka, Yuhji
AU - Tanakaya, Kohji
AU - Yasui, Yoshimasa
AU - Tanemoto, Kazuo
AU - Kashitani, Masaaki
AU - Kobayashi, Genso
PY - 1994
Y1 - 1994
N2 - In order to speculate the role of platelet in the wound healing, we examined platelet count in 27 patients who showed anastomotic leakage after gastrointestinal surgery. Thirty-nine patients who did not show leakage were served as control. Results were as follows: (1) The maximal values of platelet after surgery correlated with the surgical invasion. (2) Platelet count showed biphasic pattern after surgery. At first platelet count decreased. Then the count increased and reached its maximal values in the 2nd week in the control group. However, the maximal values were obtained in the 3rd week in the case of the patients with leakage. After that, platelet count decreased to normal level in healing stage. This tendency was more prominent in early leakage group than delayed leakage group. (3) The changing pattern of platelet count after surgery did not coincide with that of white cell count. White cell count was normal in 10 out of 27 (37%) in leakage cases. However, the platelet count in these cases increased in 9 out of 10 (90%). Therefore, it is concluded that the maximum of platelet after surgery reflects surgical invasion well. The changing pattern of platelet count after surgery is useful in speculating healing stage and detecting anastomotic leakage early.
AB - In order to speculate the role of platelet in the wound healing, we examined platelet count in 27 patients who showed anastomotic leakage after gastrointestinal surgery. Thirty-nine patients who did not show leakage were served as control. Results were as follows: (1) The maximal values of platelet after surgery correlated with the surgical invasion. (2) Platelet count showed biphasic pattern after surgery. At first platelet count decreased. Then the count increased and reached its maximal values in the 2nd week in the control group. However, the maximal values were obtained in the 3rd week in the case of the patients with leakage. After that, platelet count decreased to normal level in healing stage. This tendency was more prominent in early leakage group than delayed leakage group. (3) The changing pattern of platelet count after surgery did not coincide with that of white cell count. White cell count was normal in 10 out of 27 (37%) in leakage cases. However, the platelet count in these cases increased in 9 out of 10 (90%). Therefore, it is concluded that the maximum of platelet after surgery reflects surgical invasion well. The changing pattern of platelet count after surgery is useful in speculating healing stage and detecting anastomotic leakage early.
KW - anastomotic leakage
KW - cytokine
KW - platelet count
KW - wound healing
UR - http://www.scopus.com/inward/record.url?scp=85007669280&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85007669280&partnerID=8YFLogxK
U2 - 10.11261/iryo1946.48.483
DO - 10.11261/iryo1946.48.483
M3 - Article
AN - SCOPUS:85007669280
VL - 48
SP - 483
EP - 487
JO - IRYO - Japanese Journal of National Medical Services
JF - IRYO - Japanese Journal of National Medical Services
SN - 0021-1699
IS - 7
ER -