The catalytic activity of glass beads, silica gels and anion-exchange resins modified with metal-porphines in the oxidative reaction of NADH

Akimasa Iwado, Masaki Mifune, Rumiko Harada, Junko Oda, Noriko Motohashi, Yutaka Saito

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Silica gel and glass beads were modified using the acid chloride of metal-tetrakis(4-carboxyphenyl)porphine (M-TCPP) through a peptide bond, and an anion-exchange resin was modified with M-TCPP by electrostatic interaction and physical adsorption. The carriers modified with Co3+-TCPP proved to accelerate the following redox reaction: NADH + O2 carriers modified with Co-TCPP NADH+H2O2. The formation of hydrogen peroxide was confirmed by means of a colored reaction. The glass heads modified with Co3+-TCPP exhibited the strongest activity among the tested carriers, and were expected to be useful practically as a solid catalyst for the formation of hydrogen peroxide from NADH.

Original languageEnglish
Pages (from-to)1301-1304
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume47
Issue number9
Publication statusPublished - Sep 1999

Fingerprint

Anion Exchange Resins
Silica Gel
NAD
Glass
Catalyst activity
Metals
Hydrogen Peroxide
Redox reactions
Fused silica
Coulomb interactions
Static Electricity
Adsorption
Oxidation-Reduction
Chlorides
Head
Peptides
Catalysts
Acids
tetracarboxyphenylporphine
porphine

Keywords

  • Determination
  • Hydrogen peroxide
  • Metal-porphine
  • Modified carrier
  • NADH
  • Oxidative catalysis

ASJC Scopus subject areas

  • Chemistry(all)
  • Organic Chemistry
  • Drug Discovery
  • Pharmacology

Cite this

The catalytic activity of glass beads, silica gels and anion-exchange resins modified with metal-porphines in the oxidative reaction of NADH. / Iwado, Akimasa; Mifune, Masaki; Harada, Rumiko; Oda, Junko; Motohashi, Noriko; Saito, Yutaka.

In: Chemical and Pharmaceutical Bulletin, Vol. 47, No. 9, 09.1999, p. 1301-1304.

Research output: Contribution to journalArticle

Iwado, Akimasa ; Mifune, Masaki ; Harada, Rumiko ; Oda, Junko ; Motohashi, Noriko ; Saito, Yutaka. / The catalytic activity of glass beads, silica gels and anion-exchange resins modified with metal-porphines in the oxidative reaction of NADH. In: Chemical and Pharmaceutical Bulletin. 1999 ; Vol. 47, No. 9. pp. 1301-1304.
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AU - Motohashi, Noriko

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