TY - JOUR
T1 - The biological attributes, genome architecture and packaging of diverse multi-component fungal viruses
AU - Sato, Yukiyo
AU - Castón, José R.
AU - Suzuki, Nobuhiro
N1 - Funding Information:
This study was supported in part by Yomogi Inc. and Grants-in-Aid for Scientific Research (A) and on Innovative Areas from the Japanese Ministry of Education, Culture, Sports, Science, and Technology ( KAKENHI 25252011 and 16H06436 , 16H06429 , and 16K21723 to N.S.). Funding to JRC was from the Spanish Ministry of Economy and Competitivity ( BFU2017-88736-R (l. 572) ) and the Comunidad Autónoma de Madrid ( S2013/MIT-2807 ). We also wish to thank Dr. Hideki Kondo for their fruitful discussion and sharing unpublished data with us.
Funding Information:
This study was supported in part by Yomogi Inc. and Grants-in-Aid for Scientific Research (A) and on Innovative Areas from the Japanese Ministry of Education, Culture, Sports, Science, and Technology (KAKENHI 25252011 and 16H06436, 16H06429, and 16K21723 to N.S.). Funding to JRC was from the Spanish Ministry of Economy and Competitivity (BFU2017-88736-R (l. 572)) and the Comunidad Autónoma de Madrid (S2013/MIT-2807). We also wish to thank Dr. Hideki Kondo for their fruitful discussion and sharing unpublished data with us.
Publisher Copyright:
© 2018 Elsevier B.V.
PY - 2018/12
Y1 - 2018/12
N2 - Many fungal viruses or mycoviruses have multi-segmented, rather than single-segmented, genomes. This multi-segment nature is frequently possessed by double-stranded RNA viruses, which include members of the Chrysoviridae, Quadriviridae, Megabirnaviridae, Partitiviridae, and Reoviridae families, and unassigned groups. Their genome segments are often packaged separately with the exception of mycoreoviruses, which are multi-segmented but mono-particulate viruses. These multi-segmented fungal dsRNA viruses, as exemplified by reoviruses, have been extensively studied among structural biologists, and contributed to discoveries of novel virion structures. Multi-component systems, interactions of viruses with subviral agents such as satellite and defective RNAs as typified by the yeast killer, and the rule-breaking neo-virus lifestyle exhibited by a capsidless single-stranded RNA virus hosted in an unrelated double-stranded RNA virus are also discussed. Fungal multi-segmented viruses and multicomponent virus systems would continue to provide virologists with interesting future challenges.
AB - Many fungal viruses or mycoviruses have multi-segmented, rather than single-segmented, genomes. This multi-segment nature is frequently possessed by double-stranded RNA viruses, which include members of the Chrysoviridae, Quadriviridae, Megabirnaviridae, Partitiviridae, and Reoviridae families, and unassigned groups. Their genome segments are often packaged separately with the exception of mycoreoviruses, which are multi-segmented but mono-particulate viruses. These multi-segmented fungal dsRNA viruses, as exemplified by reoviruses, have been extensively studied among structural biologists, and contributed to discoveries of novel virion structures. Multi-component systems, interactions of viruses with subviral agents such as satellite and defective RNAs as typified by the yeast killer, and the rule-breaking neo-virus lifestyle exhibited by a capsidless single-stranded RNA virus hosted in an unrelated double-stranded RNA virus are also discussed. Fungal multi-segmented viruses and multicomponent virus systems would continue to provide virologists with interesting future challenges.
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U2 - 10.1016/j.coviro.2018.07.009
DO - 10.1016/j.coviro.2018.07.009
M3 - Review article
C2 - 30081358
AN - SCOPUS:85050874384
SN - 1879-6257
VL - 33
SP - 55
EP - 65
JO - Current Opinion in Virology
JF - Current Opinion in Virology
ER -