The accessory limb model: An alternative experimental system of limb regeneration

Tetsuya Endo, David M. Gardiner, Aki Makanae, Akira Satoh

Research output: Contribution to journalArticle

11 Citations (Scopus)


Accessory limb model (ALM) was developed as an experimental model and functional assay for limb regeneration. The ALM provides several ways to identify pathways and test for signaling molecules that regulate limb regeneration. Here, we summarize the history of the ALM and describe the specific details involved in inducing ectopic blastemas and limbs from a skin wound on the side of the arm.

Original languageEnglish
Pages (from-to)101-113
Number of pages13
JournalMethods in Molecular Biology
Publication statusPublished - Jan 1 2015



  • Axolotl
  • Limb regeneration
  • Nerve
  • Salamander
  • Slow-release sustained bead

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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