The accelerator-based boron neutron capture reaction evaluation system for head and neck cancer

Shou Wang, Kazuyo Igawa, Ryo Ogawara, Mitsuru Suda, Tsuyoshi Hamano, Soichiro Ibaragi, Tadashi Hanafusa, Yasuaki Ichikawa, Akira Sasaki

Research output: Contribution to journalArticlepeer-review

Abstract

The purpose of this study is to assess accelerator-based boron neutron capture reaction (BNCR) in human tumor cell lines by colony formation assay and modified high density survival assay (HDS assay). The results of post irradiation survival rate in human oral squamous cell carcinoma and osteosarcoma using both assays were similar. Therefore, HDS assay would be efficient to evaluate BNCR in not only tumor cells but also in normal cells as BNCT screening.

Original languageEnglish
Article number109271
JournalApplied Radiation and Isotopes
Volume165
DOIs
Publication statusPublished - Nov 2020

Keywords

  • BNCR
  • BPA
  • Head and neck cancer
  • Osteosarcoma
  • SCC

ASJC Scopus subject areas

  • Radiation

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