TY - JOUR
T1 - The 2020 revised comprehensive diagnostic (RCD) criteria for IgG4-RD
AU - the Research Program for Intractable Disease by the Ministry of Health, Labor and Welfare (MHLW) Japan.
AU - Umehara, Hisanori
AU - Okazaki, Kazuichi
AU - Kawa, Shigeyuki
AU - Takahashi, Hiroki
AU - Goto, Hiroshi
AU - Matsui, Shoko
AU - Ishizaka, Nobukazu
AU - Akamizu, Takashi
AU - Sato, Yasuharu
AU - Kawano, Mitsuhiro
N1 - Funding Information:
This study was supported by Health and Labor Sciences Research grants (K.O.) for Intractable Diseases, from the Minister of Labor and Welfare of Japan and MHLW Research Program on Rare and Intractable Diseases Grant Number JPMH20FC1040. The authors thank Dr. Kenji Notohara (Kurashiki Hospital) for insightful comments and pictures of storiform fibrosis and obliterative phlebitis. We also thank Prof. Shigeo Nakamura (Nagoya University) and Prof. Tadashi Yoshino (Okayama University) for the special comments of pathological information of IgG4-RD.
Publisher Copyright:
© 2021 Japan College of Rheumatology. Published by Informa UK Limited, trading as Taylor & Francis Group.
PY - 2021
Y1 - 2021
N2 - IgG4-related disease (IgG4-RD) is a fascinating clinical entity first reported in this century in Japan, and includes a wide variety of diseases, such as formerly named Mikulicz's disease (MD), autoimmune pancreatitis (AIP), interstitial nephritis, prostatitis and retroperitoneal fibrosis. The Japanese IgG4 team organized by the Ministry of Health, Labor and Welfare (MHLW) of Japan has published the first criteria, comprehensive diagnostic (CD) criteria for IgG-RD 2011. Thereafter, IgG4-RD has been accepted widely and many cases have been reported from all over the world. Several problems have arisen in clinical practice, however, including the difficulty obtaining biopsy samples, and the sensitivity and specificity in cut off level of serum IgG4 and impaired immunostaining of IgG4. Given these situations, the Japanese IgG4 team has updated the 2011 comprehensive diagnostic criteria for IgG4-RD and propose the 2020 revised comprehensive diagnostic (RCD) criteria for IgG4-RD, which consists of 3 domains; 1) Clinical and radiological features, 2) Serological diagnosis and 3) Pathological diagnosis. In addition, the new pathological diagnosis is composed by three sub-items including storiform fibrosis and obliterative phlebitis.
AB - IgG4-related disease (IgG4-RD) is a fascinating clinical entity first reported in this century in Japan, and includes a wide variety of diseases, such as formerly named Mikulicz's disease (MD), autoimmune pancreatitis (AIP), interstitial nephritis, prostatitis and retroperitoneal fibrosis. The Japanese IgG4 team organized by the Ministry of Health, Labor and Welfare (MHLW) of Japan has published the first criteria, comprehensive diagnostic (CD) criteria for IgG-RD 2011. Thereafter, IgG4-RD has been accepted widely and many cases have been reported from all over the world. Several problems have arisen in clinical practice, however, including the difficulty obtaining biopsy samples, and the sensitivity and specificity in cut off level of serum IgG4 and impaired immunostaining of IgG4. Given these situations, the Japanese IgG4 team has updated the 2011 comprehensive diagnostic criteria for IgG4-RD and propose the 2020 revised comprehensive diagnostic (RCD) criteria for IgG4-RD, which consists of 3 domains; 1) Clinical and radiological features, 2) Serological diagnosis and 3) Pathological diagnosis. In addition, the new pathological diagnosis is composed by three sub-items including storiform fibrosis and obliterative phlebitis.
KW - IgG4-RD
KW - Mikulicz’s disease
KW - autoimmune pancreatitis
KW - criteria
KW - diagnosis
KW - orbital disease
KW - sclerosing cholangitis
UR - http://www.scopus.com/inward/record.url?scp=85100146152&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85100146152&partnerID=8YFLogxK
U2 - 10.1080/14397595.2020.1859710
DO - 10.1080/14397595.2020.1859710
M3 - Article
C2 - 33274670
AN - SCOPUS:85100146152
VL - 31
SP - 529
EP - 533
JO - Japanese Journal of Rheumatology
JF - Japanese Journal of Rheumatology
SN - 1439-7595
IS - 3
ER -