Taxpropellane, the first example of a taxane with an unprecedented 6/5/5/6/4/5-membered ring hexacyclic skeleton ([3.3.2]propellane), was isolated from the needles of Taxus canadensis. This compound would be derived from a normal 6/8/6 taxane by a [2+2] cycloaddition reaction between the 3,4- and 11,12-double bonds.
- Fused-ring systems
- Structure elucidation
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry