Taxpropellane: A novel taxane with an unprecedented polycyclic skeleton from the needles of Taxus canadensis

Man Li Zhang; Mei Dong; Chang Hong Huo; Li Geng Li; Françoise Sauriol; Qing Wen Shi; Yu Cheng Gu; Hidefumi Makabe; Hiromasa Kiyota

doi:10.1002/ejoc.200800587

Taxpropellane: A novel taxane with an unprecedented polycyclic skeleton from the needles of Taxus canadensis

Man Li Zhang, Mei Dong, Chang Hong Huo, Li Geng Li, Françoise Sauriol, Qing Wen Shi, Yu Cheng Gu, Hidefumi Makabe, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Taxpropellane, the first example of a taxane with an unprecedented 6/5/5/6/4/5-membered ring hexacyclic skeleton ([3.3.2]propellane), was isolated from the needles of Taxus canadensis. This compound would be derived from a normal 6/8/6 taxane by a [2+2] cycloaddition reaction between the 3,4- and 11,12-double bonds.

Original language	English
Pages (from-to)	5414-5417
Number of pages	4
Journal	European Journal of Organic Chemistry
Issue number	32
DOIs	https://doi.org/10.1002/ejoc.200800587
Publication status	Published - Nov 1 2008
Externally published	Yes

Keywords

Fused-ring systems
Propellanes
Structure elucidation
Terpenoids

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Organic Chemistry

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10.1002/ejoc.200800587

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title = "Taxpropellane: A novel taxane with an unprecedented polycyclic skeleton from the needles of Taxus canadensis",

abstract = "Taxpropellane, the first example of a taxane with an unprecedented 6/5/5/6/4/5-membered ring hexacyclic skeleton ([3.3.2]propellane), was isolated from the needles of Taxus canadensis. This compound would be derived from a normal 6/8/6 taxane by a [2+2] cycloaddition reaction between the 3,4- and 11,12-double bonds.",

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doi = "10.1002/ejoc.200800587",

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T2 - A novel taxane with an unprecedented polycyclic skeleton from the needles of Taxus canadensis

AU - Zhang, Man Li

AU - Dong, Mei

AU - Huo, Chang Hong

AU - Li, Li Geng

AU - Sauriol, Françoise

AU - Shi, Qing Wen

AU - Gu, Yu Cheng

AU - Makabe, Hidefumi

AU - Kiyota, Hiromasa

PY - 2008/11/1

Y1 - 2008/11/1

N2 - Taxpropellane, the first example of a taxane with an unprecedented 6/5/5/6/4/5-membered ring hexacyclic skeleton ([3.3.2]propellane), was isolated from the needles of Taxus canadensis. This compound would be derived from a normal 6/8/6 taxane by a [2+2] cycloaddition reaction between the 3,4- and 11,12-double bonds.

AB - Taxpropellane, the first example of a taxane with an unprecedented 6/5/5/6/4/5-membered ring hexacyclic skeleton ([3.3.2]propellane), was isolated from the needles of Taxus canadensis. This compound would be derived from a normal 6/8/6 taxane by a [2+2] cycloaddition reaction between the 3,4- and 11,12-double bonds.

KW - Fused-ring systems

KW - Propellanes

KW - Structure elucidation

KW - Terpenoids

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ER -

Taxpropellane: A novel taxane with an unprecedented polycyclic skeleton from the needles of Taxus canadensis

Abstract

Keywords

ASJC Scopus subject areas

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