Taurospongins B and C, new acetylenic fatty acid derivatives possessing a taurine amide residue from a marine sponge of the family Spongiidae

Takaaki Kubota; Haruna Suzuki; Azusa Takahashi-Nakaguchi; Jane Fromont; Tohru Gonoi; Jun'Ichi Kobayashi

doi:10.1039/c3ra47796g

Taurospongins B and C, new acetylenic fatty acid derivatives possessing a taurine amide residue from a marine sponge of the family Spongiidae

Takaaki Kubota, Haruna Suzuki, Azusa Takahashi-Nakaguchi, Jane Fromont, Tohru Gonoi, Jun'Ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Two new acetylenic fatty acid derivatives possessing a taurine amide residue, taurospongins B (1) and C (2), have been isolated from an Okinawan marine sponge of the family Spongiidae. The gross structures of 1 and 2 were elucidated on the basis of their spectral data, especially 2D NMR and FABMS/MS data. The absolute configurations for 1 and 2 were established by chemical means. Taurospongin C (2) showed inhibitory activity against Cryptococcus neoformans.

Original language	English
Pages (from-to)	11073-11079
Number of pages	7
Journal	RSC Advances
Volume	4
Issue number	22
DOIs	https://doi.org/10.1039/c3ra47796g
Publication status	Published - 2014
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)
Chemical Engineering(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1039/c3ra47796g

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Taurospongins B and C, new acetylenic fatty acid derivatives possessing a taurine amide residue from a marine sponge of the family Spongiidae. / Kubota, Takaaki; Suzuki, Haruna; Takahashi-Nakaguchi, Azusa; Fromont, Jane; Gonoi, Tohru; Kobayashi, Jun'Ichi.

In: RSC Advances, Vol. 4, No. 22, 2014, p. 11073-11079.

Research output: Contribution to journal › Article › peer-review

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AU - Fromont, Jane

AU - Gonoi, Tohru

AU - Kobayashi, Jun'Ichi

PY - 2014

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AB - Two new acetylenic fatty acid derivatives possessing a taurine amide residue, taurospongins B (1) and C (2), have been isolated from an Okinawan marine sponge of the family Spongiidae. The gross structures of 1 and 2 were elucidated on the basis of their spectral data, especially 2D NMR and FABMS/MS data. The absolute configurations for 1 and 2 were established by chemical means. Taurospongin C (2) showed inhibitory activity against Cryptococcus neoformans.

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Taurospongins B and C, new acetylenic fatty acid derivatives possessing a taurine amide residue from a marine sponge of the family Spongiidae

Abstract

ASJC Scopus subject areas

UN SDGs

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