Taurospongins B and C, new acetylenic fatty acid derivatives possessing a taurine amide residue from a marine sponge of the family Spongiidae

Takaaki Kubota, Haruna Suzuki, Azusa Takahashi-Nakaguchi, Jane Fromont, Tohru Gonoi, Jun'Ichi Kobayashi

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Two new acetylenic fatty acid derivatives possessing a taurine amide residue, taurospongins B (1) and C (2), have been isolated from an Okinawan marine sponge of the family Spongiidae. The gross structures of 1 and 2 were elucidated on the basis of their spectral data, especially 2D NMR and FABMS/MS data. The absolute configurations for 1 and 2 were established by chemical means. Taurospongin C (2) showed inhibitory activity against Cryptococcus neoformans.

Original languageEnglish
Pages (from-to)11073-11079
Number of pages7
JournalRSC Advances
Volume4
Issue number22
DOIs
Publication statusPublished - 2014
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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