Tattoo skin reaction as a skin manifestation of systemic sarcoidosis

Tomoyuki Mukai, Dan Fujiwara, Tomoko Miyake, Shunichi Fujita, Shin Morizane, Yoshitaka Morita

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


A 41-year-old man presented with itching of the skin surrounding his tattoos, blurred vision, fever, general fatigue, and arthralgia. Physical examination revealed skin bulges confined to the tattoo ink lines. Histological analyses of the skin revealed non-caseating granulomas surrounding the tattoo inks. Together with other clinical manifestations including uveitis, lymph nodes swelling, and elevated serum angiotensin-converting enzyme and lysozyme, he was diagnosed with systemic sarcoidosis. The administration of prednisolone alleviated the sarcoidosis-related symptoms, including skin changes. This case illustrates that skin changes on tattoos can be a presenting manifestation of systemic sarcoidosis and that skin biopsy is useful in early diagnosis.

Original languageEnglish
Pages (from-to)167-171
Number of pages5
JournalModern Rheumatology Case Reports
Issue number1
Publication statusPublished - 2021
Externally publishedYes


  • corticosteroid
  • cutaneous sarcoidosis
  • Sarcoidosis
  • skin biopsy
  • tattoo

ASJC Scopus subject areas

  • Rheumatology


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