Tannins of Hamamelidaceous Plants. III.1) Isorugosins A, B and D, New Ellagitannins from Liquidambar formosana

Tsutomu Hatano, Reimo Kira, Taeko Yasuhara, Takuo Okuda

Research output: Contribution to journalArticlepeer-review

31 Citations (Scopus)


A new dimeric hydrolyzable tannin named isorugosin D (11), and two new monomeric tannins of related structures, isorugosin A (10) and isorugosin B (1), were isolated from the leaf of Liquidambar formosana hance (hamamelidaceae). The orientation of the valoneoyl group at 0-4 and 0-6 of the glucose core in isorugosins A, B and D was found to be different from that of rugosin A (7), rugosin B (6) and rugosin D (18), and the orientations of this group in the tannins of both type were confirmed on the basis of the two-dimensional nuclear magnetic resonance spectrum (long-range 1H-13C correlation spectrum) of rugosin A (7).

Original languageEnglish
Pages (from-to)3920-3927
Number of pages8
JournalChemical and Pharmaceutical Bulletin
Issue number10
Publication statusPublished - 1988


  • Hamamelidaceae
  • Liquidambar formosana
  • centrifugal partition chromatography
  • dimeric hydrolyzable tannin
  • ellagitannin
  • isorugosin A
  • isorugosin B
  • isorugosin D
  • rugosin A
  • tannin

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery


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