Tannins of Cornaceous Plants. I. Cornusiins A, B and C, Dimeric Monomeric and Trimeric Hydrolyzable Tannins from Cornus officinalis, and Orientation of Valoneoyl Group in Related Tannins

Tsutomu Hatano, Noboru Ogawa, Reiko Kira, Taeko Yasuhara, Takuo Okuda

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Cornusiin A (1), cornusiin B (2) and cornusiin C (3), new dimeric, monomeric and trimeric hydrolyzable tannins, were isolated from the fruits of Cornus officinalis (Cornaceae). Their structures, including the orientation of the valoneoyl group in 1 and 3, were established on the basis of chemical and spectroscopic data. 2,3-Di-O-galloyl-D-glucose (7), l,2,3-tri-0-galloyl-/?-D-glucose, l,2,6-tri-0-galloyl-/f-D-glucose, l,2,3,6-tetra-0-gaIloyl-/?-D-glucose, gemin D (5), isoterchebin, tellimagrandin I (6) and tellimagrandin II were also isolated from the fruits. The orientation of the valoneoyl group in camptothin A (14) and that in camptothin B (15), which had been isolated from Camptotheca acuminata (Nyssaceae), were also determined based on that in 1.

Original languageEnglish
Pages (from-to)2083-2090
Number of pages8
JournalChemical and Pharmaceutical Bulletin
Issue number8
Publication statusPublished - Jan 1 1989



  • Cornus officinalis Camptotheca acuminata tannin
  • cornusiin A cornusiin B: cornusiin C: oenothein C: camptothin A: camptothin B:
  • hydrolyzable tannin

ASJC Scopus subject areas

  • Chemistry(all)
  • Drug Discovery

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