Takayasu's arteritis associated with ulcerative colitis; genetic factors in this association

Yoshitaka Morita, Masahiro Yamamura, Kinichiro Suwaki, Atsushi Mima, Tsutomu Ishizu, Mamoru Hirohata, Naoki Kashihara, Hirofumi Makino, Zensuke Ota

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)


Both ulcerative colitis and Takayasu's arteritis are thought to be organ-specific immune-mediated inflammatory diseases. We present the rare case of a 23-year-old woman with a 4-year history of ulcerative colitis who developed Takayasu's arteritis one month after giving birth. She was found to carry the human leukocyte antigens (HLA)-B52 and DR2, which were previously noted to be associated with these inflammatory conditions in the Japanese population. The pathogenic relevance of this haplotype to the concomitant development of these two conditions is discussed.

Original languageEnglish
Pages (from-to)574-578
Number of pages5
JournalInternal Medicine
Issue number7
Publication statusPublished - Jul 1996


  • HLA-DR2
  • human leukocyte antigens (HLA)-B52

ASJC Scopus subject areas

  • Internal Medicine


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