Systematical characterization of phase behaviors and membrane properties of fatty acid/didecyldimethylammonium bromide vesicles

Keishi Suga, Tomoya Yokoi, Dai Kondo, Keita Hayashi, Seiichi Morita, Yukihiro Okamoto, Toshinori Shimanouchi, Hiroshi Umakoshi

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Fatty acids (FAs) are known to form vesicle structures, depending on the surrounding pH conditions. In this study, we prepared vesicles by mixing FAs and a cationic surfactant, and then investigated their physicochemical properties using fluorescence spectroscopy and dielectric dispersion analysis (DDA). The assemblies formed from oleic acid (OA) and linoleic acid (LA) were modified by adding didecyldimethylammonium bromide (DDAB). The phase state of FA/DDAB mixtures was investigated with pH titration curves and turbidity measurements. The trigonal diagram of FA/ionized FA/DDAB was successfully drawn to understand the phase behaviors of FA/DDAB systems. The analysis of fluidities in the interior of the membrane with use of 1,6-diphenyl-1,3,5-hexatriene (DPH) indicated that the membrane fluidities of OA/DDAB and LA/DDAB at pH 8.5 slightly decreased in proportion to the molar ratio of DDAB in FA/DDAB systems. The fluorescent probe 6-lauroyl-2-dimethylamino naphthalene (Laurdan) indicated that the LA vesicle possessed a dehydrated surface, while the OA vesicle surface was hydrated. Modification of LA vesicles with DDAB induced the hydration of membrane surfaces, whereas modification of OA vesicles by DDAB had the opposite effect. DDA analysis indicated that the membrane surfaces were hydrated in the presence of DDAB, suggesting that the surface properties of FA vesicles are tunable by DDAB modification.

Original languageEnglish
Pages (from-to)12721-12728
Number of pages8
JournalLangmuir
Volume30
Issue number43
DOIs
Publication statusPublished - Nov 4 2014

Fingerprint

fatty acids
Phase behavior
Fatty acids
bromides
Fatty Acids
membranes
Membranes
Linoleic acid
Oleic acid
oleic acid
Linoleic Acid
Oleic Acid
Fluidity
acids
Permittivity
didecyldimethylammonium
Cationic surfactants
Fluorescence spectroscopy
Turbidity
Naphthalene

ASJC Scopus subject areas

  • Electrochemistry
  • Condensed Matter Physics
  • Surfaces and Interfaces
  • Materials Science(all)
  • Spectroscopy

Cite this

Suga, K., Yokoi, T., Kondo, D., Hayashi, K., Morita, S., Okamoto, Y., ... Umakoshi, H. (2014). Systematical characterization of phase behaviors and membrane properties of fatty acid/didecyldimethylammonium bromide vesicles. Langmuir, 30(43), 12721-12728. https://doi.org/10.1021/la503331r

Systematical characterization of phase behaviors and membrane properties of fatty acid/didecyldimethylammonium bromide vesicles. / Suga, Keishi; Yokoi, Tomoya; Kondo, Dai; Hayashi, Keita; Morita, Seiichi; Okamoto, Yukihiro; Shimanouchi, Toshinori; Umakoshi, Hiroshi.

In: Langmuir, Vol. 30, No. 43, 04.11.2014, p. 12721-12728.

Research output: Contribution to journalArticle

Suga, K, Yokoi, T, Kondo, D, Hayashi, K, Morita, S, Okamoto, Y, Shimanouchi, T & Umakoshi, H 2014, 'Systematical characterization of phase behaviors and membrane properties of fatty acid/didecyldimethylammonium bromide vesicles', Langmuir, vol. 30, no. 43, pp. 12721-12728. https://doi.org/10.1021/la503331r
Suga, Keishi ; Yokoi, Tomoya ; Kondo, Dai ; Hayashi, Keita ; Morita, Seiichi ; Okamoto, Yukihiro ; Shimanouchi, Toshinori ; Umakoshi, Hiroshi. / Systematical characterization of phase behaviors and membrane properties of fatty acid/didecyldimethylammonium bromide vesicles. In: Langmuir. 2014 ; Vol. 30, No. 43. pp. 12721-12728.
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