Synthetic study on 13-oxyingenol: construction of the full carbon framework

Ichiro Hayakawa, Yuki Asuma, Takayuki Ohyoshi, Kenta Aoki, Hideo Kigoshi

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

13-Oxyingenol is a diterpenoid isolated from Euphorbia kansui, and its derivatives have strong anti-HIV activity. We achieved the construction of inside-outside framework of 13-oxyingenol by using ring-closing olefin metathesis.

Original languageEnglish
Pages (from-to)6221-6224
Number of pages4
JournalTetrahedron Letters
Volume48
Issue number35
DOIs
Publication statusPublished - Aug 27 2007
Externally publishedYes

Keywords

  • 13-Oxyingenol
  • Anti-HIV activity
  • Ring-closing olefin metathesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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