Synthetic studies towards optically active 13-oxyingenol via asymmetric cyclopropanation

Ichiro Hayakawa, Yamato Miyazawa, Takayuki Ohyoshi, Yuki Asuma, Kenta Aoki, Hideo Kigoshi

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The enantioselective synthesis of a seven-membered enone compound, the key intermediate of our previous synthesis of the inside-outside framework of 13-oxyingenol in racemic form, was achieved by using asymmetric cyclopropanation and reductive deoxygenation as key steps.

Original languageEnglish
Pages (from-to)769-777
Number of pages9
JournalSynthesis
Issue number5
DOIs
Publication statusPublished - Feb 2 2011
Externally publishedYes

Keywords

  • 13-oxyingenol
  • asymmetric cyclopropanation
  • chiral aza-semicorrin ligand
  • intramolecular -aldol reaction
  • reductive deoxygenation

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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  • Cite this

    Hayakawa, I., Miyazawa, Y., Ohyoshi, T., Asuma, Y., Aoki, K., & Kigoshi, H. (2011). Synthetic studies towards optically active 13-oxyingenol via asymmetric cyclopropanation. Synthesis, (5), 769-777. https://doi.org/10.1055/s-0030-1259430