Biselides A and B are cytotoxic marine polyketides. We have achieved synthesis of the C-1-C-15 segment of biselides A and B by using Stille coupling and regioselective oxidative cleavage as key steps. Furthermore, we constructed the α,β-unsaturated lactone part of biselide E by using a similar strategy.
- Regioselective oxidative cleavage
- Stille coupling
ASJC Scopus subject areas
- Organic Chemistry
- Drug Discovery