equation presented Didemniserinolipid B (1) R = H; proposed structure R = SO3Na; revised structure En route to proving the absolute and relative stereochemistry, through synthesis, of (+)-didemniserinolipid B (1), the first natural serinolipid isolated from a tunicate Didemnum sp., it was discovered that the isolated natural product was in fact the 31-sulfate configured 8R,9R,10R,-13S,30S. This structural reassignment was only possible after the development of a microwave-assisted method for the sulfation of unreactive hydroxyl groups.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry