Abstract
The spiroacetal [C(9)-C(20)] fragments of spirofungins A and B, antibiotics isolated from Streptomyces violaceusniger Tü 4113, were prepared from a known bromo alcohol derived from (S)-citronellal, using thermodynamically controlled iodolactonization and spiroacetalization as the key steps.
Original language | English |
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Pages (from-to) | 337-343 |
Number of pages | 7 |
Journal | Heterocyclic Communications |
Volume | 21 |
Issue number | 6 |
DOIs | |
Publication status | Published - Dec 1 2015 |
Keywords
- Streptomyces violaceusniger Tü 4113
- acetylide
- antibiotics
- iodolactonization
- selenolactonization
- spiroacetalization
- spirofungins A and B
- synthesis
ASJC Scopus subject areas
- Organic Chemistry