Effect of turpentine induced inflammation on the serum content of C9 was studied in guinea pigs. A transient increase in the serum content as measured by an immunochemical method of Mancini was observed in all guinea pigs suffering from inflammation. The serum C9 reached a maximum of approximately 200% of the initial serum level at 4 days after the injection of inflammatory agent. From studies involving incorporation of [14C]leucine into C9, it was shown that the rate of C9 synthesis in guinea pigs with turpentine induced inflammation was increased significantly over that observed in normal guinea pigs.
|Number of pages||7|
|Journal||International Archives of Allergy and Applied Immunology|
|Publication status||Published - 1974|
ASJC Scopus subject areas
- Immunology and Allergy