Synthesis of the E ring segment of ciguatoxin CTX3C via the negishi coupling of cyclic ketene acetal triflates

Kengo Shiroma; Hiroyoshi Takamura; Isao Kadota

doi:10.3987/COM-12-S(N)117

Synthesis of the E ring segment of ciguatoxin CTX3C via the negishi coupling of cyclic ketene acetal triflates

Kengo Shiroma, Hiroyoshi Takamura, Isao Kadota

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Stereocontrolled synthesis of the E ring segment of ciguatoxin CTX3C was performed via the Negishi coupling of cyclic ketene acetal triflates. Transformation of 8-membered lactones to the corresponding ketene acetal triflates was found to be affected by the protective groups of the substrates.

Original language	English
Pages (from-to)	997-1001
Number of pages	5
Journal	Heterocycles
Volume	86
Issue number	2
DOIs	https://doi.org/10.3987/COM-12-S(N)117
Publication status	Published - Dec 1 2012

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

Access to Document

10.3987/COM-12-S(N)117

Cite this

@article{d3135597d7a44b5aace856b7d9c9763c,

title = "Synthesis of the E ring segment of ciguatoxin CTX3C via the negishi coupling of cyclic ketene acetal triflates",

abstract = "Stereocontrolled synthesis of the E ring segment of ciguatoxin CTX3C was performed via the Negishi coupling of cyclic ketene acetal triflates. Transformation of 8-membered lactones to the corresponding ketene acetal triflates was found to be affected by the protective groups of the substrates.",

author = "Kengo Shiroma and Hiroyoshi Takamura and Isao Kadota",

year = "2012",

month = dec,

day = "1",

doi = "10.3987/COM-12-S(N)117",

language = "English",

volume = "86",

pages = "997--1001",

journal = "Heterocycles",

issn = "0385-5414",

publisher = "Japan Institute of Heterocyclic Chemistry",

number = "2",

}

TY - JOUR

T1 - Synthesis of the E ring segment of ciguatoxin CTX3C via the negishi coupling of cyclic ketene acetal triflates

AU - Shiroma, Kengo

AU - Takamura, Hiroyoshi

AU - Kadota, Isao

PY - 2012/12/1

Y1 - 2012/12/1

N2 - Stereocontrolled synthesis of the E ring segment of ciguatoxin CTX3C was performed via the Negishi coupling of cyclic ketene acetal triflates. Transformation of 8-membered lactones to the corresponding ketene acetal triflates was found to be affected by the protective groups of the substrates.

AB - Stereocontrolled synthesis of the E ring segment of ciguatoxin CTX3C was performed via the Negishi coupling of cyclic ketene acetal triflates. Transformation of 8-membered lactones to the corresponding ketene acetal triflates was found to be affected by the protective groups of the substrates.

UR - http://www.scopus.com/inward/record.url?scp=84880602168&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84880602168&partnerID=8YFLogxK

U2 - 10.3987/COM-12-S(N)117

DO - 10.3987/COM-12-S(N)117

M3 - Article

AN - SCOPUS:84880602168

SN - 0385-5414

VL - 86

SP - 997

EP - 1001

JO - Heterocycles

JF - Heterocycles

IS - 2

ER -

Synthesis of the E ring segment of ciguatoxin CTX3C via the negishi coupling of cyclic ketene acetal triflates

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this