Synthesis of the CD ring system of paclitaxel by atom-transfer radical annulation reaction

Takehiko Yoshimitsu; Hideyuki Nakajima; Hiroto Nagaoka

doi:10.1016/S0040-4039(02)02058-0

Synthesis of the CD ring system of paclitaxel by atom-transfer radical annulation reaction

Takehiko Yoshimitsu, Hideyuki Nakajima, Hiroto Nagaoka

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Atom-transfer radical annulation of diene derived from D-glucose under Kharasch conditions provided access to the fully functionalized CD ring system of paclitaxel.

Original language	English
Pages (from-to)	8587-8590
Number of pages	4
Journal	Tetrahedron Letters
Volume	43
Issue number	47
DOIs	https://doi.org/10.1016/S0040-4039(02)02058-0
Publication status	Published - Nov 18 2002
Externally published	Yes

Keywords

Annulation
Radicals and radical reactions
Taxoids

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(02)02058-0

Cite this

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title = "Synthesis of the CD ring system of paclitaxel by atom-transfer radical annulation reaction",

abstract = "Atom-transfer radical annulation of diene derived from D-glucose under Kharasch conditions provided access to the fully functionalized CD ring system of paclitaxel.",

keywords = "Annulation, Radicals and radical reactions, Taxoids",

author = "Takehiko Yoshimitsu and Hideyuki Nakajima and Hiroto Nagaoka",

year = "2002",

month = nov,

day = "18",

doi = "10.1016/S0040-4039(02)02058-0",

language = "English",

volume = "43",

pages = "8587--8590",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "47",

}

TY - JOUR

T1 - Synthesis of the CD ring system of paclitaxel by atom-transfer radical annulation reaction

AU - Yoshimitsu, Takehiko

AU - Nakajima, Hideyuki

AU - Nagaoka, Hiroto

PY - 2002/11/18

Y1 - 2002/11/18

N2 - Atom-transfer radical annulation of diene derived from D-glucose under Kharasch conditions provided access to the fully functionalized CD ring system of paclitaxel.

AB - Atom-transfer radical annulation of diene derived from D-glucose under Kharasch conditions provided access to the fully functionalized CD ring system of paclitaxel.

KW - Annulation

KW - Radicals and radical reactions

KW - Taxoids

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UR - http://www.scopus.com/inward/citedby.url?scp=0037131741&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(02)02058-0

DO - 10.1016/S0040-4039(02)02058-0

M3 - Article

AN - SCOPUS:0037131741

SN - 0040-4039

VL - 43

SP - 8587

EP - 8590

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 47

ER -

Synthesis of the CD ring system of paclitaxel by atom-transfer radical annulation reaction

Abstract

Keywords

ASJC Scopus subject areas

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