Synthesis of the CD ring system of paclitaxel by atom-transfer radical annulation reaction

Takehiko Yoshimitsu, Hideyuki Nakajima, Hiroto Nagaoka

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Atom-transfer radical annulation of diene derived from D-glucose under Kharasch conditions provided access to the fully functionalized CD ring system of paclitaxel.

Original languageEnglish
Pages (from-to)8587-8590
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number47
DOIs
Publication statusPublished - Nov 18 2002
Externally publishedYes

Keywords

  • Annulation
  • Radicals and radical reactions
  • Taxoids

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthesis of the CD ring system of paclitaxel by atom-transfer radical annulation reaction'. Together they form a unique fingerprint.

  • Cite this