Synthesis of southern (C1′-C11′) fragment of pamamycin-635A

Ayako Miura, Hiromasa Kiyota, Shigefumi Kuwahara

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The synthesis of the southern (C1′-C11′) fragment of pamamycin-635A, isolated from Streptomyces alboniger, was achieved via an Evans aldol reaction, a cis-selective iodoetherification and a stereospecific deiodination as the key steps.

Original languageEnglish
Pages (from-to)1061-1067
Number of pages7
JournalTetrahedron
Volume61
Issue number5
DOIs
Publication statusPublished - Jan 31 2005
Externally publishedYes

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Streptomyces
pamamycin
3-hydroxybutanal

Keywords

  • Evans aldol reaction
  • Iodoetherification
  • Pamamycins
  • Synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Synthesis of southern (C1′-C11′) fragment of pamamycin-635A. / Miura, Ayako; Kiyota, Hiromasa; Kuwahara, Shigefumi.

In: Tetrahedron, Vol. 61, No. 5, 31.01.2005, p. 1061-1067.

Research output: Contribution to journalArticle

Miura, Ayako ; Kiyota, Hiromasa ; Kuwahara, Shigefumi. / Synthesis of southern (C1′-C11′) fragment of pamamycin-635A. In: Tetrahedron. 2005 ; Vol. 61, No. 5. pp. 1061-1067.
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