Synthesis of southern (C1′-C11′) fragment of pamamycin-635A

Ayako Miura, Hiromasa Kiyota, Shigefumi Kuwahara

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

The synthesis of the southern (C1′-C11′) fragment of pamamycin-635A, isolated from Streptomyces alboniger, was achieved via an Evans aldol reaction, a cis-selective iodoetherification and a stereospecific deiodination as the key steps.

Original languageEnglish
Pages (from-to)1061-1067
Number of pages7
JournalTetrahedron
Volume61
Issue number5
DOIs
Publication statusPublished - Jan 31 2005
Externally publishedYes

Keywords

  • Evans aldol reaction
  • Iodoetherification
  • Pamamycins
  • Synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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