Synthesis of PDMS-based porous materials for biomedical applications

T. Yabuta, E. P. Bescher, J. D. Mackenzie, K. Tsuru, Satoshi Hayakawa, A. Osaka

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Abstract

Polydimethylsiloxane (PDMS) and tetraethoxysilane (TEOS)-based porous organically modified silicates (ORMOSILs) for biomedical applications were synthesized through a sol-gel process, using sucrose particles as templates. These materials were characterized by 29Si CP-MAS NMR spectroscopy, thin film X-ray diffraction, and scanning electron microscopy. Their bioactivity was evaluated using a simulated body fluid (SBF) of Kokubo recipe. These materials had a bimodal porous structure with pores of 300-500 μm and 10-50 μm in diameter. NMR showed that the silanol groups of the PDMS chain cross-linked to silica derived from the hydrolysis and condensation of TEOS. The samples containing Ca(II) exhibited apatite deposition on the pore walls within 3 days in SBF.

Original languageEnglish
Pages (from-to)1219-1222
Number of pages4
JournalJournal of Sol-Gel Science and Technology
Volume26
Issue number1-3
DOIs
Publication statusPublished - Jan 2003

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Keywords

  • Apatite deposition
  • Bioactivity
  • Ormosil
  • Porous hybrid
  • Simulated body fluid

ASJC Scopus subject areas

  • Ceramics and Composites

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