Synthesis of PDMS-based porous materials for biomedical applications

T. Yabuta, E. P. Bescher, J. D. Mackenzie, K. Tsuru, Satoshi Hayakawa, A. Osaka

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

Polydimethylsiloxane (PDMS) and tetraethoxysilane (TEOS)-based porous organically modified silicates (ORMOSILs) for biomedical applications were synthesized through a sol-gel process, using sucrose particles as templates. These materials were characterized by 29Si CP-MAS NMR spectroscopy, thin film X-ray diffraction, and scanning electron microscopy. Their bioactivity was evaluated using a simulated body fluid (SBF) of Kokubo recipe. These materials had a bimodal porous structure with pores of 300-500 μm and 10-50 μm in diameter. NMR showed that the silanol groups of the PDMS chain cross-linked to silica derived from the hydrolysis and condensation of TEOS. The samples containing Ca(II) exhibited apatite deposition on the pore walls within 3 days in SBF.

Original languageEnglish
Pages (from-to)1219-1222
Number of pages4
JournalJournal of Sol-Gel Science and Technology
Volume26
Issue number1-3
DOIs
Publication statusPublished - Jan 2003

Fingerprint

body fluids
Body fluids
porous materials
Polydimethylsiloxane
Porous materials
porosity
Silicates
Apatites
nuclear magnetic resonance
sucrose
Apatite
Sugar (sucrose)
Polymers
apatites
sol-gel processes
synthesis
Bioactivity
Silicon Dioxide
Sol-gel process
Nuclear magnetic resonance spectroscopy

Keywords

  • Apatite deposition
  • Bioactivity
  • Ormosil
  • Porous hybrid
  • Simulated body fluid

ASJC Scopus subject areas

  • Ceramics and Composites

Cite this

Synthesis of PDMS-based porous materials for biomedical applications. / Yabuta, T.; Bescher, E. P.; Mackenzie, J. D.; Tsuru, K.; Hayakawa, Satoshi; Osaka, A.

In: Journal of Sol-Gel Science and Technology, Vol. 26, No. 1-3, 01.2003, p. 1219-1222.

Research output: Contribution to journalArticle

Yabuta, T. ; Bescher, E. P. ; Mackenzie, J. D. ; Tsuru, K. ; Hayakawa, Satoshi ; Osaka, A. / Synthesis of PDMS-based porous materials for biomedical applications. In: Journal of Sol-Gel Science and Technology. 2003 ; Vol. 26, No. 1-3. pp. 1219-1222.
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