Synthesis of molecular tweezers bearing pentafluorophenyl and several pendant aryl groups. Effective application of the modified Suzuki-Miyaura coupling reaction

Toshinobu Korenaga, Takahiro Kosaki, Yusuke Kawauchi, Tadashi Ema, Takashi Sakai

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A molecular tweezer bearing two pentafluorophenyl groups 2b and its o-methylated aryl homologue 2c were newly synthesized by the slight modification of the known procedure. The low yield in the introduction of pentafluorophenyl group to the precursor dibromide 6 was improved by application of the modified Suzuki-Miyaura coupling reaction using C6F5B(OH)2 with Pd2(dba)3/P(t-Bu)3/CsF/Ag2O catalytic system, which was recently developed by us.

Original languageEnglish
Pages (from-to)604-609
Number of pages6
JournalJournal of Fluorine Chemistry
Volume127
Issue number4-5 SPEC. ISS.
DOIs
Publication statusPublished - May 1 2006

Keywords

  • Molecular tweezer
  • Pentafluorophenyl group
  • Stacking interaction
  • Suzuki-Miyaura coupling

ASJC Scopus subject areas

  • Biochemistry
  • Environmental Chemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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