Synthesis of Macrotetrolide α, a Designed Polynactin Analog Composed of (+)- and (-)-Bishomononactic Acids

Tadaatsu Hanadate; Hiromasa Kiyota; Takayuki Oritani

doi:10.1271/bbb.65.2118

Synthesis of Macrotetrolide α, a Designed Polynactin Analog Composed of (+)- and (-)-Bishomononactic Acids

Tadaatsu Hanadate, Hiromasa Kiyota, Takayuki Oritani

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Macrotetrolide α, a designed analog of polynactin composed of (+)- and (-)-bishomononactic acids, was synthesized. These monomers were prepared via optical resolution of the corresponding (S)-O-acetylmandelates. Assembly of the monomers to macrotetrolide a look seven steps without any loss of the intermediates.

Original language	English
Pages (from-to)	2118-2120
Number of pages	3
Journal	Bioscience, Biotechnology and Biochemistry
Volume	65
Issue number	9
DOIs	https://doi.org/10.1271/bbb.65.2118
Publication status	Published - Sep 2001
Externally published	Yes

Keywords

Bishomononactate
Macrotetrolide
Optical resolution
Polynactin
Total synthesis

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

Access to Document

10.1271/bbb.65.2118

Fingerprint Dive into the research topics of 'Synthesis of Macrotetrolide α, a Designed Polynactin Analog Composed of (+)- and (-)-Bishomononactic Acids'. Together they form a unique fingerprint.

Cite this

@article{e47f2ff891ab48ac915197e7e6982e5a,

title = "Synthesis of Macrotetrolide α, a Designed Polynactin Analog Composed of (+)- and (-)-Bishomononactic Acids",

abstract = "Macrotetrolide α, a designed analog of polynactin composed of (+)- and (-)-bishomononactic acids, was synthesized. These monomers were prepared via optical resolution of the corresponding (S)-O-acetylmandelates. Assembly of the monomers to macrotetrolide a look seven steps without any loss of the intermediates.",

keywords = "Bishomononactate, Macrotetrolide, Optical resolution, Polynactin, Total synthesis",

author = "Tadaatsu Hanadate and Hiromasa Kiyota and Takayuki Oritani",

year = "2001",

month = sep,

doi = "10.1271/bbb.65.2118",

language = "English",

volume = "65",

pages = "2118--2120",

journal = "Bioscience, Biotechnology and Biochemistry",

issn = "0916-8451",

publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",

number = "9",

}

TY - JOUR

T1 - Synthesis of Macrotetrolide α, a Designed Polynactin Analog Composed of (+)- and (-)-Bishomononactic Acids

AU - Hanadate, Tadaatsu

AU - Kiyota, Hiromasa

AU - Oritani, Takayuki

PY - 2001/9

Y1 - 2001/9

N2 - Macrotetrolide α, a designed analog of polynactin composed of (+)- and (-)-bishomononactic acids, was synthesized. These monomers were prepared via optical resolution of the corresponding (S)-O-acetylmandelates. Assembly of the monomers to macrotetrolide a look seven steps without any loss of the intermediates.

AB - Macrotetrolide α, a designed analog of polynactin composed of (+)- and (-)-bishomononactic acids, was synthesized. These monomers were prepared via optical resolution of the corresponding (S)-O-acetylmandelates. Assembly of the monomers to macrotetrolide a look seven steps without any loss of the intermediates.

KW - Bishomononactate

KW - Macrotetrolide

KW - Optical resolution

KW - Polynactin

KW - Total synthesis

UR - http://www.scopus.com/inward/record.url?scp=0035460365&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035460365&partnerID=8YFLogxK

U2 - 10.1271/bbb.65.2118

DO - 10.1271/bbb.65.2118

M3 - Article

C2 - 11676034

AN - SCOPUS:0035460365

VL - 65

SP - 2118

EP - 2120

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

SN - 0916-8451

IS - 9

ER -

Synthesis of Macrotetrolide α, a Designed Polynactin Analog Composed of (+)- and (-)-Bishomononactic Acids

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this