Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction

Hitoshi Abe, Masatsugu Arai, Keisuke Nishioka, Tatsuya Kida, Kazuma Shioe, Yasuo Takeuchi, Takashi Harayama

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Optically active 6,6'-dihydroxymethyl-2,2'-3,3'-4,4'-hexamethoxybiphenyl (1) was prepared via the Pd-mediated biaryl coupling reaction of a phenyl benzoate derivative and the following enantioselective lactone opening reaction.

Original languageEnglish
Pages (from-to)291-303
Number of pages13
JournalHeterocycles
Volume76
Issue number1
DOIs
Publication statusPublished - 2008

Fingerprint

Benzoates
Palladium
Lactones
Derivatives
diphenyl

ASJC Scopus subject areas

  • Analytical Chemistry
  • Organic Chemistry
  • Pharmacology

Cite this

Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction. / Abe, Hitoshi; Arai, Masatsugu; Nishioka, Keisuke; Kida, Tatsuya; Shioe, Kazuma; Takeuchi, Yasuo; Harayama, Takashi.

In: Heterocycles, Vol. 76, No. 1, 2008, p. 291-303.

Research output: Contribution to journalArticle

Abe, Hitoshi ; Arai, Masatsugu ; Nishioka, Keisuke ; Kida, Tatsuya ; Shioe, Kazuma ; Takeuchi, Yasuo ; Harayama, Takashi. / Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction. In: Heterocycles. 2008 ; Vol. 76, No. 1. pp. 291-303.
@article{e6a06279dd9548d8b66ea671ea8d0a48,
title = "Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction",
abstract = "Optically active 6,6'-dihydroxymethyl-2,2'-3,3'-4,4'-hexamethoxybiphenyl (1) was prepared via the Pd-mediated biaryl coupling reaction of a phenyl benzoate derivative and the following enantioselective lactone opening reaction.",
author = "Hitoshi Abe and Masatsugu Arai and Keisuke Nishioka and Tatsuya Kida and Kazuma Shioe and Yasuo Takeuchi and Takashi Harayama",
year = "2008",
doi = "10.3987/COM-08-S(N)8",
language = "English",
volume = "76",
pages = "291--303",
journal = "Heterocycles",
issn = "0385-5414",
publisher = "Japan Institute of Heterocyclic Chemistry",
number = "1",

}

TY - JOUR

T1 - Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction

AU - Abe, Hitoshi

AU - Arai, Masatsugu

AU - Nishioka, Keisuke

AU - Kida, Tatsuya

AU - Shioe, Kazuma

AU - Takeuchi, Yasuo

AU - Harayama, Takashi

PY - 2008

Y1 - 2008

N2 - Optically active 6,6'-dihydroxymethyl-2,2'-3,3'-4,4'-hexamethoxybiphenyl (1) was prepared via the Pd-mediated biaryl coupling reaction of a phenyl benzoate derivative and the following enantioselective lactone opening reaction.

AB - Optically active 6,6'-dihydroxymethyl-2,2'-3,3'-4,4'-hexamethoxybiphenyl (1) was prepared via the Pd-mediated biaryl coupling reaction of a phenyl benzoate derivative and the following enantioselective lactone opening reaction.

UR - http://www.scopus.com/inward/record.url?scp=77955676901&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955676901&partnerID=8YFLogxK

U2 - 10.3987/COM-08-S(N)8

DO - 10.3987/COM-08-S(N)8

M3 - Article

AN - SCOPUS:77955676901

VL - 76

SP - 291

EP - 303

JO - Heterocycles

JF - Heterocycles

SN - 0385-5414

IS - 1

ER -