Synthesis of glaziovianin A: A potent antitumor isoflavone

Ichiro Hayakawa, Akiyuki Ikedo, Hideo Kigoshi

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Glaziovianin A (1) is a novel isoflavone derivative isolated from the leaves of the Brazilian tree Astelia glazioviana. Glaziovianin A (1) showed cytotoxic activity and was suggested to be an inhibitor of tubulin polymerization. We achieved the total synthesis of glaziovianin A (1) by using the Suzuki-Miyaura coupling as a key step.

Original languageEnglish
Pages (from-to)1382-1383
Number of pages2
JournalChemistry Letters
Volume36
Issue number11
DOIs
Publication statusPublished - Nov 5 2007
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)

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