Synthesis of functionalized phospholane oxides and phosphorinane oxides from 1,4- and 1,5-di-o-mesyloxy compounds

Tadashi Hanaya, Karsten Schürrle, Hiroshi Yamamoto

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Treatment of 1,4-di-O-mesyl-2,3-di-O-methyl-L-threitol (8b) with phenylphosphine in the presence of sodium hydride in DMSO, followed by the action of hydrogen peroxide, afforded 3,4-dimethoxy-l-phenylphospholane 1-oxide (7), while the same treatment of 1,5-di-O-mesyl-2,3,4-tri-O-methyl-meso-xylitol (11b) provided 2,3,4-trimethoxy-1-phenylphosphorinane 1-oxide (14).

Original languageEnglish
Pages (from-to)283-294
Number of pages12
JournalHeterocycles
Volume69
Issue number1
Publication statusPublished - Dec 1 2006

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Oxides
Xylitol
Dimethyl Sulfoxide
Hydrogen Peroxide
threitol
sodium hydride

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of functionalized phospholane oxides and phosphorinane oxides from 1,4- and 1,5-di-o-mesyloxy compounds. / Hanaya, Tadashi; Schürrle, Karsten; Yamamoto, Hiroshi.

In: Heterocycles, Vol. 69, No. 1, 01.12.2006, p. 283-294.

Research output: Contribution to journalArticle

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