Synthesis of (—)-ent-Altholactone, (+)-7a-epi-Altholactone, (—)-ent-Isoaltholactone and (—)-7a-epi-Isoaltholactone from 2,3-O-Cyclohexylidene-D-glyceraldehyde

Akira Hiratate; Hiromasa Kiyota; Takayuki Oritani

doi:10.1584/jpestics.26.361

Synthesis of (—)-ent-Altholactone, (+)-7a-epi-Altholactone, (—)-ent-Isoaltholactone and (—)-7a-epi-Isoaltholactone from 2,3-O-Cyclohexylidene-D-glyceraldehyde

Akira Hiratate, Hiromasa Kiyota, Takayuki Oritani

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Synthesis of the diastereomers of (+)-altholactone, an antitumor acetogenin from various Goniothalamus species, was achieved. Four isomers including 3a,7a-trans-fused analogs were synthesized from 2,3-O-cyclohexylidene-D-glyceraldehyde via twice separation of diastereomers.

Original language	English
Pages (from-to)	361-365
Number of pages	5
Journal	Journal of Pesticide Science
Volume	26
Issue number	4
DOIs	https://doi.org/10.1584/jpestics.26.361
Publication status	Published - 2001
Externally published	Yes

Keywords

altholactone
goniothalenol
isoaltholactone
total synthesis

ASJC Scopus subject areas

Insect Science
Health, Toxicology and Mutagenesis

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10.1584/jpestics.26.361

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title = "Synthesis of (—)-ent-Altholactone, (+)-7a-epi-Altholactone, (—)-ent-Isoaltholactone and (—)-7a-epi-Isoaltholactone from 2,3-O-Cyclohexylidene-D-glyceraldehyde",

abstract = "Synthesis of the diastereomers of (+)-altholactone, an antitumor acetogenin from various Goniothalamus species, was achieved. Four isomers including 3a,7a-trans-fused analogs were synthesized from 2,3-O-cyclohexylidene-D-glyceraldehyde via twice separation of diastereomers.",

keywords = "altholactone, goniothalenol, isoaltholactone, total synthesis",

author = "Akira Hiratate and Hiromasa Kiyota and Takayuki Oritani",

year = "2001",

doi = "10.1584/jpestics.26.361",

language = "English",

volume = "26",

pages = "361--365",

journal = "Journal of Pesticide Sciences",

issn = "1348-589X",

publisher = "Pesticide Science Society of Japan",

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TY - JOUR

T1 - Synthesis of (—)-ent-Altholactone, (+)-7a-epi-Altholactone, (—)-ent-Isoaltholactone and (—)-7a-epi-Isoaltholactone from 2,3-O-Cyclohexylidene-D-glyceraldehyde

AU - Hiratate, Akira

AU - Kiyota, Hiromasa

AU - Oritani, Takayuki

PY - 2001

Y1 - 2001

N2 - Synthesis of the diastereomers of (+)-altholactone, an antitumor acetogenin from various Goniothalamus species, was achieved. Four isomers including 3a,7a-trans-fused analogs were synthesized from 2,3-O-cyclohexylidene-D-glyceraldehyde via twice separation of diastereomers.

AB - Synthesis of the diastereomers of (+)-altholactone, an antitumor acetogenin from various Goniothalamus species, was achieved. Four isomers including 3a,7a-trans-fused analogs were synthesized from 2,3-O-cyclohexylidene-D-glyceraldehyde via twice separation of diastereomers.

KW - altholactone

KW - goniothalenol

KW - isoaltholactone

KW - total synthesis

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U2 - 10.1584/jpestics.26.361

DO - 10.1584/jpestics.26.361

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EP - 365

JO - Journal of Pesticide Sciences

JF - Journal of Pesticide Sciences

IS - 4

ER -

Synthesis of (—)-ent-Altholactone, (+)-7a-epi-Altholactone, (—)-ent-Isoaltholactone and (—)-7a-epi-Isoaltholactone from 2,3-O-Cyclohexylidene-D-glyceraldehyde

Abstract

Keywords

ASJC Scopus subject areas

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