Synthesis of carbocyclic and acyclic nucleosides possessing 2-fluoroadenine derivatives and their inhibitory activities against Plasmodium falciparum SAH hydrolase.

Yukio Kitade, Hiroharu Kojima, Fazila Zulfiqur, Saori Yabe, Daisuke Yamagiwa, Yasutomo Ito, Masayuki Nakanishi, Yoshihito Ueno, Hye-Sook Kim, Yusuke Wataya

Research output: Chapter in Book/Report/Conference proceeding › Chapter

3 Citations (Scopus)

Abstract

Carbocyclic and acyclic nucleosides possessing 2-fluoroadenine, such as 2-fluoronoraristeromycin (6) and 2-fluoro-9-[(2S,3R)-2,3,4-trihydroxy-butyl-1-yl]adenine (8), were synthesized and their inhibitory activities against human and Plasmodium falciparum recombinant SAH hydrolase were investigated.

Original languageEnglish
Title of host publicationNucleic acids research. Supplement (2001)
Pages5-6
Number of pages2
Edition3
Publication statusPublished - 2003
Externally publishedYes

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Adenosylhomocysteinase
Adenine
Plasmodium falciparum
Nucleosides
Human Activities
2-fluoronoraristeromycin
2-fluoroadenine

Cite this

Kitade, Y., Kojima, H., Zulfiqur, F., Yabe, S., Yamagiwa, D., Ito, Y., ... Wataya, Y. (2003). Synthesis of carbocyclic and acyclic nucleosides possessing 2-fluoroadenine derivatives and their inhibitory activities against Plasmodium falciparum SAH hydrolase. In Nucleic acids research. Supplement (2001) (3 ed., pp. 5-6)

Synthesis of carbocyclic and acyclic nucleosides possessing 2-fluoroadenine derivatives and their inhibitory activities against Plasmodium falciparum SAH hydrolase. / Kitade, Yukio; Kojima, Hiroharu; Zulfiqur, Fazila; Yabe, Saori; Yamagiwa, Daisuke; Ito, Yasutomo; Nakanishi, Masayuki; Ueno, Yoshihito; Kim, Hye-Sook; Wataya, Yusuke.

Nucleic acids research. Supplement (2001). 3. ed. 2003. p. 5-6.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Kitade, Y, Kojima, H, Zulfiqur, F, Yabe, S, Yamagiwa, D, Ito, Y, Nakanishi, M, Ueno, Y, Kim, H-S & Wataya, Y 2003, Synthesis of carbocyclic and acyclic nucleosides possessing 2-fluoroadenine derivatives and their inhibitory activities against Plasmodium falciparum SAH hydrolase. in Nucleic acids research. Supplement (2001). 3 edn, pp. 5-6.
Kitade Y, Kojima H, Zulfiqur F, Yabe S, Yamagiwa D, Ito Y et al. Synthesis of carbocyclic and acyclic nucleosides possessing 2-fluoroadenine derivatives and their inhibitory activities against Plasmodium falciparum SAH hydrolase. In Nucleic acids research. Supplement (2001). 3 ed. 2003. p. 5-6
Kitade, Yukio ; Kojima, Hiroharu ; Zulfiqur, Fazila ; Yabe, Saori ; Yamagiwa, Daisuke ; Ito, Yasutomo ; Nakanishi, Masayuki ; Ueno, Yoshihito ; Kim, Hye-Sook ; Wataya, Yusuke. / Synthesis of carbocyclic and acyclic nucleosides possessing 2-fluoroadenine derivatives and their inhibitory activities against Plasmodium falciparum SAH hydrolase. Nucleic acids research. Supplement (2001). 3. ed. 2003. pp. 5-6
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AU - Kitade, Yukio

AU - Kojima, Hiroharu

AU - Zulfiqur, Fazila

AU - Yabe, Saori

AU - Yamagiwa, Daisuke

AU - Ito, Yasutomo

AU - Nakanishi, Masayuki

AU - Ueno, Yoshihito

AU - Kim, Hye-Sook

AU - Wataya, Yusuke

PY - 2003

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