Synthesis of both enantiomers of altholactone, isoaltholactone and 5-hydroxygoniothalamin from tri-O-acetyl-D-glucal, and their biological activities

Akira Hiratate, Hiromasa Kiyota, Toshiro Noshita, Ryo Takeuchi, Takayuki Oritani

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Both enantiomers of altholactone, isoaltholactone and 5-hydroxygoniothalamin were synthesized from tri-O-acetyl-D-glucal, and biological activities of altholactones were examined. For brine shrimp, the configuration of 3-hydroxy group at convex site was important for lethal activity, while (2S,3S)-configuration was inhibitory to lettuce germination.

Original languageEnglish
Pages (from-to)366-370
Number of pages5
JournalJournal of Pesticide Science
Volume26
Issue number4
Publication statusPublished - 2001
Externally publishedYes

Fingerprint

Calcium Gluconate
enantiomers
Artemia
lettuce
bioactive properties
germination
Lettuce
synthesis
Germination
altholactone

Keywords

  • 5-hydroxygoniothalamin
  • Altholactone
  • Isoaltholactone
  • Total synthesis
  • Tri-O-acetyl-D-glucal

ASJC Scopus subject areas

  • Insect Science

Cite this

Synthesis of both enantiomers of altholactone, isoaltholactone and 5-hydroxygoniothalamin from tri-O-acetyl-D-glucal, and their biological activities. / Hiratate, Akira; Kiyota, Hiromasa; Noshita, Toshiro; Takeuchi, Ryo; Oritani, Takayuki.

In: Journal of Pesticide Science, Vol. 26, No. 4, 2001, p. 366-370.

Research output: Contribution to journalArticle

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AU - Oritani, Takayuki

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