Synthesis of arnottin I through a palladium-mediated aryl-aryl coupling reaction

Takashi Harayama, Hirotake Yasuda, Toshihiko Akiyama, Yasuo Takeuchi, Hitoshi Abe

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

6H-Dibenzo[b,d]pyran-6-one, 6H-benzo[d]naphtho[1,2-b]pyran-6-one, and their derivatives were prepared via the palladium mediated aryl-aryl coupling reaction of aryl ortho-halobenzoate. The short step synthesis of arnottin I (1) was achieved by this method.

Original languageEnglish
Pages (from-to)861-864
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume48
Issue number6
Publication statusPublished - Jun 2000

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Keywords

  • Arnottin I
  • Biaryl coupling reaction
  • Palladium reagent

ASJC Scopus subject areas

  • Drug Discovery
  • Organic Chemistry
  • Chemistry(all)
  • Pharmacology

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