Synthesis of (-)-actinonin

Shin Ichi Inoue, Hiromi Nishioka, Hitoshi Abe, Takashi Harayama, Yasuo Takeuchi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Synthesis of (-)-actinonin in 17% overall yield was accomplished in seven steps via the formation of an isoimide derivative as the key intermediate. The synthesis was carried out using commercially available dimethyl maleate without the use of a highly expensive reagent.

Original languageEnglish
Pages (from-to)1705-1710
Number of pages6
JournalSynthesis
Issue number11
DOIs
Publication statusPublished - May 9 2011

Keywords

  • PDF inhibitor
  • actinonin
  • antibacterial agent
  • catalytic hydrogenation
  • total synthesis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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