Synthesis of (-)-actinonin

Shin Ichi Inoue; Hiromi Nishioka; Hitoshi Abe; Takashi Harayama; Yasuo Takeuchi

doi:10.1055/s-0030-1260461

Synthesis of (-)-actinonin

Shin Ichi Inoue, Hiromi Nishioka, Hitoshi Abe, Takashi Harayama, Yasuo Takeuchi

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

Synthesis of (-)-actinonin in 17% overall yield was accomplished in seven steps via the formation of an isoimide derivative as the key intermediate. The synthesis was carried out using commercially available dimethyl maleate without the use of a highly expensive reagent.

Original language	English
Pages (from-to)	1705-1710
Number of pages	6
Journal	Synthesis
Issue number	11
DOIs	https://doi.org/10.1055/s-0030-1260461
Publication status	Published - May 9 2011

Keywords

PDF inhibitor
actinonin
antibacterial agent
catalytic hydrogenation
total synthesis

ASJC Scopus subject areas

Catalysis
Organic Chemistry

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10.1055/s-0030-1260461

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@article{36b870276d964ed8b7ea159ad785f4d4,

title = "Synthesis of (-)-actinonin",

abstract = "Synthesis of (-)-actinonin in 17% overall yield was accomplished in seven steps via the formation of an isoimide derivative as the key intermediate. The synthesis was carried out using commercially available dimethyl maleate without the use of a highly expensive reagent.",

keywords = "PDF inhibitor, actinonin, antibacterial agent, catalytic hydrogenation, total synthesis",

author = "Inoue, {Shin Ichi} and Hiromi Nishioka and Hitoshi Abe and Takashi Harayama and Yasuo Takeuchi",

year = "2011",

month = may,

day = "9",

doi = "10.1055/s-0030-1260461",

language = "English",

pages = "1705--1710",

journal = "Synthesis",

issn = "0039-7881",

publisher = "Georg Thieme Verlag",

number = "11",

}

TY - JOUR

T1 - Synthesis of (-)-actinonin

AU - Inoue, Shin Ichi

AU - Nishioka, Hiromi

AU - Abe, Hitoshi

AU - Harayama, Takashi

AU - Takeuchi, Yasuo

PY - 2011/5/9

Y1 - 2011/5/9

N2 - Synthesis of (-)-actinonin in 17% overall yield was accomplished in seven steps via the formation of an isoimide derivative as the key intermediate. The synthesis was carried out using commercially available dimethyl maleate without the use of a highly expensive reagent.

AB - Synthesis of (-)-actinonin in 17% overall yield was accomplished in seven steps via the formation of an isoimide derivative as the key intermediate. The synthesis was carried out using commercially available dimethyl maleate without the use of a highly expensive reagent.

KW - PDF inhibitor

KW - actinonin

KW - antibacterial agent

KW - catalytic hydrogenation

KW - total synthesis

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UR - http://www.scopus.com/inward/citedby.url?scp=79956346877&partnerID=8YFLogxK

U2 - 10.1055/s-0030-1260461

DO - 10.1055/s-0030-1260461

M3 - Article

AN - SCOPUS:79956346877

SN - 0039-7881

SP - 1705

EP - 1710

JO - Synthesis

JF - Synthesis

IS - 11

ER -

Synthesis of (-)-actinonin

Abstract

Keywords

ASJC Scopus subject areas

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