Synthesis of A-ring fragments of 1α,25-dihydroxyvitamin D3 and taxane diterpenoids: Effective construction of conjugated formylcyclohexene frameworks from isoxazolines

Teruhiko Ishikawa, Shushiro Ikeda, Masataka Ibe, Seiki Saito

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

This paper have delineated the effectiveness of [3+2] cycloaddition process in the synthesis of multifunctional 6-membered rings. The novel synthesis of chiral A-ring fragment of 1α,25-dihydroxyvitamin D3 and also a novel route to A-ring fragment of taxane diterpenoids have been established.

Original languageEnglish
Pages (from-to)5869-5882
Number of pages14
JournalTetrahedron
Volume54
Issue number22
DOIs
Publication statusPublished - May 28 1998

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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