Synthesis of a novel artemisinin analogue having potent antimalarial activity

Kiyosei Takasu, Ruriko Katagiri, Yuko Tanaka, Masahiro Toyota, Hye Sook Kim, Yusuke Wataya, Masataka Ihara

Research output: Contribution to journal › Article

9 Citations (Scopus)

Abstract

An artemisinin analogue containing 1,2,4-trioxane structure was designed and synthesized. The compound exhibited significant and selective in vitro antimalarial activity.

Original languageEnglish
Pages (from-to)607-610
Number of pages4
JournalHeterocycles
Volume54
Issue number2
DOIs
Publication statusPublished - Feb 1 2001

Keywords

  • 1,2,4-Trioxane
  • Antimalarial Activity
  • Artemisinin
  • Octalone

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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    Takasu, K., Katagiri, R., Tanaka, Y., Toyota, M., Kim, H. S., Wataya, Y., & Ihara, M. (2001). Synthesis of a novel artemisinin analogue having potent antimalarial activity. Heterocycles, 54(2), 607-610. https://doi.org/10.3987/com-00-s(i)91