Abstract
One-pot synthesis of 3-allyl- and 3-benzyl-Δ3-cephems through a sequential reductive 1,2-elimination/addition/cyclization of 3, 4- disubstituted 2-[2- oxo-3-phenylacetamido-4-(phenylsulfonylthio)azetidin- 1- yl]-2-butenoates was successfully performed by treatment with allyl and benzyl halides in an Mn/NiCl2(bpy)/AlCl3/N-methyl-2-pyrroridinone (NMP) system.
Original language | English |
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Pages (from-to) | 633-642 |
Number of pages | 10 |
Journal | Heterocycles |
Volume | 52 |
Issue number | 2 |
DOIs | |
Publication status | Published - Feb 1 2000 |
ASJC Scopus subject areas
- Analytical Chemistry
- Pharmacology
- Organic Chemistry