Synthesis of 2,4-dideoxy-4-[(S)-methyl- and (R)-cyclohexylphosphinyl]-α,β-D-erythro-pentofuranoses. The first P-in-ring sugar analogues of 2-deoxy-D-ribofuranose type

Hiroshi Yamamoto, Ayashi Noguchi, Kenji Torii, Keiji Ohno, Tadashi Hanaya, Heizan Kawamoto, Saburo Inokawa

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Starting with 3-deoxy-1,2-O-isopropylidene-α-D-ribo-hexofuranose, methyl 2,4-dideoxy-4-[(methoxy)methyl- and cyclohexylphosphinyl]-D-glycero-pentopyranosides were prepared in a 9 step sequence (20-25% overall yield). These were converted into the title compounds, which were characterized as the 1,3,5-tri-O-acetates.

Original languageEnglish
Pages (from-to)1575-1576
Number of pages2
JournalChemistry Letters
Volume17
Issue number9
DOIs
Publication statusPublished - Jan 1 1988

ASJC Scopus subject areas

  • Chemistry(all)

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