Abstract
Use of a rhodium catalyst with (R)-(S)-BPPFA ligand allows efficient synthesis of sila[n]helicenes via dehydrogenative silylation of C-H bonds. By selecting the proper ligands, the current method provides the ability to prepare unsymmetrical sila[n]helicene derivatives without any oxidants. The resulting sila[6]helicene is a rare example of a five-membered ring-fused [6]helicene, which was isolated as a single pure enantiomer without substituents on the terminal benzene rings.
| Original language | English |
|---|---|
| Pages (from-to) | 4380-4383 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 18 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - Sep 2 2016 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Murai, M., Okada, R., Nishiyama, A., & Takai, K. (2016). Synthesis and Properties of Sila[n]helicenes via Dehydrogenative Silylation of C-H Bonds under Rhodium Catalysis. Organic Letters, 18(17), 4380-4383. https://doi.org/10.1021/acs.orglett.6b02134