Use of a rhodium catalyst with (R)-(S)-BPPFA ligand allows efficient synthesis of sila[n]helicenes via dehydrogenative silylation of C-H bonds. By selecting the proper ligands, the current method provides the ability to prepare unsymmetrical sila[n]helicene derivatives without any oxidants. The resulting silahelicene is a rare example of a five-membered ring-fused helicene, which was isolated as a single pure enantiomer without substituents on the terminal benzene rings.
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry