Abstract
Use of a rhodium catalyst with (R)-(S)-BPPFA ligand allows efficient synthesis of sila[n]helicenes via dehydrogenative silylation of C-H bonds. By selecting the proper ligands, the current method provides the ability to prepare unsymmetrical sila[n]helicene derivatives without any oxidants. The resulting sila[6]helicene is a rare example of a five-membered ring-fused [6]helicene, which was isolated as a single pure enantiomer without substituents on the terminal benzene rings.
| Original language | English |
|---|---|
| Pages (from-to) | 4380-4383 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 18 |
| Issue number | 17 |
| DOIs | |
| Publication status | Published - Sep 2 2016 |
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ASJC Scopus subject areas
- Biochemistry
- Medicine(all)
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
Synthesis and Properties of Sila[n]helicenes via Dehydrogenative Silylation of C-H Bonds under Rhodium Catalysis. / Murai, Masahito; Okada, Ryo; Nishiyama, Atsushi; Takai, Kazuhiko.
In: Organic Letters, Vol. 18, No. 17, 02.09.2016, p. 4380-4383.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Synthesis and Properties of Sila[n]helicenes via Dehydrogenative Silylation of C-H Bonds under Rhodium Catalysis
AU - Murai, Masahito
AU - Okada, Ryo
AU - Nishiyama, Atsushi
AU - Takai, Kazuhiko
PY - 2016/9/2
Y1 - 2016/9/2
N2 - Use of a rhodium catalyst with (R)-(S)-BPPFA ligand allows efficient synthesis of sila[n]helicenes via dehydrogenative silylation of C-H bonds. By selecting the proper ligands, the current method provides the ability to prepare unsymmetrical sila[n]helicene derivatives without any oxidants. The resulting sila[6]helicene is a rare example of a five-membered ring-fused [6]helicene, which was isolated as a single pure enantiomer without substituents on the terminal benzene rings.
AB - Use of a rhodium catalyst with (R)-(S)-BPPFA ligand allows efficient synthesis of sila[n]helicenes via dehydrogenative silylation of C-H bonds. By selecting the proper ligands, the current method provides the ability to prepare unsymmetrical sila[n]helicene derivatives without any oxidants. The resulting sila[6]helicene is a rare example of a five-membered ring-fused [6]helicene, which was isolated as a single pure enantiomer without substituents on the terminal benzene rings.
UR - http://www.scopus.com/inward/record.url?scp=84985893635&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84985893635&partnerID=8YFLogxK
U2 - 10.1021/acs.orglett.6b02134
DO - 10.1021/acs.orglett.6b02134
M3 - Article
AN - SCOPUS:84985893635
VL - 18
SP - 4380
EP - 4383
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 17
ER -