Synthesis and optical resolution of novel chiral silanols

Atsunori Mori; Fumihiko Toriyama; Hiroshi Kajiro; Kazunori Hirabayashi; Yasushi Nishihara; Tamejiro Hiyama

doi:10.1246/cl.1999.549

Synthesis and optical resolution of novel chiral silanols

Atsunori Mori, Fumihiko Toriyama, Hiroshi Kajiro, Kazunori Hirabayashi, Yasushi Nishihara, Tamejiro Hiyama

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

Silanols bearing an asymmetric center on silicon, methyl(2-phenylethenyl)(3,3,3-trifluoropropyl)silanol and methyl(phenyl)(vinyl)silanol are synthesized by alkylative cleavages of cyclic siloxanes with an organolithium. Optical resolution of their enantiomers is performed by HPLC with a chiral stationary phase column. Optical characters of thus separated enantiomers are also examined.

Original language	English
Pages (from-to)	549-550
Number of pages	2
Journal	Chemistry Letters
Issue number	7
DOIs	https://doi.org/10.1246/cl.1999.549
Publication status	Published - 1999
Externally published	Yes

ASJC Scopus subject areas

Chemistry(all)

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10.1246/cl.1999.549

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title = "Synthesis and optical resolution of novel chiral silanols",

abstract = "Silanols bearing an asymmetric center on silicon, methyl(2-phenylethenyl)(3,3,3-trifluoropropyl)silanol and methyl(phenyl)(vinyl)silanol are synthesized by alkylative cleavages of cyclic siloxanes with an organolithium. Optical resolution of their enantiomers is performed by HPLC with a chiral stationary phase column. Optical characters of thus separated enantiomers are also examined.",

author = "Atsunori Mori and Fumihiko Toriyama and Hiroshi Kajiro and Kazunori Hirabayashi and Yasushi Nishihara and Tamejiro Hiyama",

year = "1999",

doi = "10.1246/cl.1999.549",

language = "English",

pages = "549--550",

journal = "Chemistry Letters",

issn = "0366-7022",

publisher = "Chemical Society of Japan",

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T1 - Synthesis and optical resolution of novel chiral silanols

AU - Mori, Atsunori

AU - Toriyama, Fumihiko

AU - Kajiro, Hiroshi

AU - Hirabayashi, Kazunori

AU - Nishihara, Yasushi

AU - Hiyama, Tamejiro

PY - 1999

Y1 - 1999

N2 - Silanols bearing an asymmetric center on silicon, methyl(2-phenylethenyl)(3,3,3-trifluoropropyl)silanol and methyl(phenyl)(vinyl)silanol are synthesized by alkylative cleavages of cyclic siloxanes with an organolithium. Optical resolution of their enantiomers is performed by HPLC with a chiral stationary phase column. Optical characters of thus separated enantiomers are also examined.

AB - Silanols bearing an asymmetric center on silicon, methyl(2-phenylethenyl)(3,3,3-trifluoropropyl)silanol and methyl(phenyl)(vinyl)silanol are synthesized by alkylative cleavages of cyclic siloxanes with an organolithium. Optical resolution of their enantiomers is performed by HPLC with a chiral stationary phase column. Optical characters of thus separated enantiomers are also examined.

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U2 - 10.1246/cl.1999.549

DO - 10.1246/cl.1999.549

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JO - Chemistry Letters

JF - Chemistry Letters

IS - 7

ER -

Synthesis and optical resolution of novel chiral silanols

Abstract

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