Synthesis and in vitro antimalarial activity of several simple analogues of peroxyplakoric acid

He Hua Liu; Hong Xia Jin; Qi Zhang; Yi Kang Wu; Hye Sook Kim; Yusuke Wataya

doi:10.1002/cjoc.200591469

Synthesis and in vitro antimalarial activity of several simple analogues of peroxyplakoric acid

He Hua Liu, Hong Xia Jin, Qi Zhang, Yi Kang Wu, Hye Sook Kim, Yusuke Wataya

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2-dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method was also briefly examined.

Original language	English
Pages (from-to)	1469-1473
Number of pages	5
Journal	Chinese Journal of Chemistry
Volume	23
Issue number	11
DOIs	https://doi.org/10.1002/cjoc.200591469
Publication status	Published - Nov 2005

Keywords

Cyclizations
Hemiketals
Peroxides
Spiroketals

ASJC Scopus subject areas

Chemistry(all)

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10.1002/cjoc.200591469

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abstract = "Several simple analogues of peroxyplakoric acid were synthesized by using Kobayashi's method to construct the key 1,2-dioxane core and tested in vitro for antimalarial activity. The scope and limitation of the method was also briefly examined.",

keywords = "Cyclizations, Hemiketals, Peroxides, Spiroketals",

author = "Liu, {He Hua} and Jin, {Hong Xia} and Qi Zhang and Wu, {Yi Kang} and Kim, {Hye Sook} and Yusuke Wataya",

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AU - Liu, He Hua

AU - Jin, Hong Xia

AU - Zhang, Qi

AU - Wu, Yi Kang

AU - Kim, Hye Sook

AU - Wataya, Yusuke

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KW - Peroxides

KW - Spiroketals

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