Synthesis and antimalarial activity of dldeoxyfebrifugine

Yasuo Takeuchi, Shin Ichiro Tokuda, Tomoko Takagi, Midori Koike, Hitoshi Abe, Takashi Harayama, Yasuharu Shibata, Hye Sook Kim, Yusuke Wataya

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

dl-Deoxyfebrifugine (3) was synthesized from 2-piperidone (4) by two methods via the Wittig reaction of 2-hydroxypiperidine (6). The antimalarial activity of 3 was discussed.

Original languageEnglish
Pages (from-to)1869-1875
Number of pages7
JournalHeterocycles
Volume51
Issue number8
DOIs
Publication statusPublished - Aug 1 1999

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

Cite this

Takeuchi, Y., Tokuda, S. I., Takagi, T., Koike, M., Abe, H., Harayama, T., Shibata, Y., Kim, H. S., & Wataya, Y. (1999). Synthesis and antimalarial activity of dldeoxyfebrifugine. Heterocycles, 51(8), 1869-1875. https://doi.org/10.3987/COM-99-8564