Synthesis and actin-depolymerizing activity of mycalolide analogs

Kiyotake Suenaga, Saori Miya, Takeshi Kuroda, Tomohisa Handa, Kengo Kanematsu, Akira Sakakura, Hideo Kigoshi

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Mycalolide analog 4, consisting only of the side chain of mycalolide B (2), was stereoselectively synthesized and was found to have strong actin-depolymerizing activity.

Original languageEnglish
Pages (from-to)5383-5386
Number of pages4
JournalTetrahedron Letters
Volume45
Issue number28
DOIs
Publication statusPublished - Jul 5 2004
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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  • Cite this

    Suenaga, K., Miya, S., Kuroda, T., Handa, T., Kanematsu, K., Sakakura, A., & Kigoshi, H. (2004). Synthesis and actin-depolymerizing activity of mycalolide analogs. Tetrahedron Letters, 45(28), 5383-5386. https://doi.org/10.1016/j.tetlet.2004.05.078