Survival of patients treated by an autonomic nerve-preserving gastrectomy for early gastric cancer

Shinsuke Sasada, Motoki Ninomiya, Masahiko Nishizaki, Masao Harano, Yasutomo Ojima, Hiroyoshi Matsukawa, Shigehiro Shiozaki, Satoshi Ohno, Norihisa Takakura

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Purpose. Autonomic nerve preservation in a gastrectomy for gastric cancer improves the postoperative quality of life. We retrospectively examined the survival of patients treated by an autonomic nerve-preserving gastrectomy in comparison to the survival of the patients treated by a conventional gastrectomy. Methods. The survival of 385 patients treated by an autonomic nerve-preserving gastrectomy for clinical early gastric cancer (the ANP group) was compared with that of 285 patients treated by a conventional gastrectomy (non-ANP group). Results. Among the ANP group, the numbers of patients with tumor invasion to the mucosa, submucosa, and muscularis propria were 210, 166, and 9, respectively, whereas the numbers of patients with lymph node metastasis grades of N0, N1, and N2 were 360, 21, and 4, respectively. The overall 5-year survival rate of the ANP group was 94.7%, which was superior to that of the non-ANP group (90.4%; P = 0.003). The 5-year survival rates of patients with lymph node metastasis were 94.9% and 91.8% in the ANP and non-ANP groups, respectively (P = 0.733). Only 3 patients in the ANP group died from gastric cancer. Conclusions. The survival of patients treated by an autonomic nerve-preserving gastrectomy was equivalent to that of patients treated by a conventional gastrectomy, thus suggesting that an autonomic nervepreserving gastrectomy could be a useful procedure for the treatment of early gastric cancer.

Original languageEnglish
Pages (from-to)444-450
Number of pages7
JournalSurgery today
Volume40
Issue number5
DOIs
Publication statusPublished - May 1 2010
Externally publishedYes

Keywords

  • Autonomic nerve preservation
  • Gastrectomy
  • Gastric cancer
  • Survival

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'Survival of patients treated by an autonomic nerve-preserving gastrectomy for early gastric cancer'. Together they form a unique fingerprint.

  • Cite this

    Sasada, S., Ninomiya, M., Nishizaki, M., Harano, M., Ojima, Y., Matsukawa, H., Shiozaki, S., Ohno, S., & Takakura, N. (2010). Survival of patients treated by an autonomic nerve-preserving gastrectomy for early gastric cancer. Surgery today, 40(5), 444-450. https://doi.org/10.1007/s00595-009-4067-9