Surgical site infection caused by Aeromonas hydrophila presenting as necrotizing soft tissue infection after esophagectomy

Osamu Yamasaki, Eizo Takahashi, Kazuyo Noda, Nobuhiko Kanaya, Shunsuke Tanabe, Yasuhiro Shirakawa, Shin Morizane

Research output: Contribution to journalArticle

Abstract

Several virulence factors of Aeromonas such as hemolysin, proteases and lipases have been characterized. The relationship between these virulence factors and disease remains unclear. A 71-year-old man underwent thoracoscopic esophagectomy, lymph node dissection and Roux-en-Y reconstruction for esophageal cancer. On postoperative day 1, redness around the wound on the thoracic abdominal wall gradually enlarged and necrosis became apparent with septic shock. Necrotizing soft tissue infection was suspected and emergency surgical debridement was performed. Blood and wound cultures were positive for Aeromonas hydrophila. The strain was found to have hemolytic activity, proteolytic activity and extremely high elastolytic activity. In addition, the strain actively produced elastolytic metalloprotease, which may contribute to extensive tissue necrosis.

Original languageEnglish
Pages (from-to)673-676
Number of pages4
JournalJournal of Dermatology
Volume47
Issue number6
DOIs
Publication statusPublished - Jun 1 2020

Keywords

  • Aeromonas hydrophila
  • metalloprotease
  • necrotizing soft tissue infection
  • surgical site infection
  • virulence factor

ASJC Scopus subject areas

  • Dermatology

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