Surgical resection for lung cancer with infiltration of the thoracic aorta

Mitsunori Ohta, Hirohisa Hirabayasi, Hiroyuki Shiono, Masato Minami, Hajime Maeda, Hiroshi Takano, Shinichiro Miyoshi, Hikaru Matsuda

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

Objective: The purpose of this study was to evaluate the results of a combined resection of the thoracic aorta and primary lung cancer. Methods: Sixteen patients underwent thoracic aorta resection along with a left pneumonectomy (n = 6), left upper lobectomy (n = 9), or partial lung resection (n = 1), of whom 10 also received preoperative induction therapy. Cardiopulmonary bypass was used in 10 patients, and a passive shunt between the ascending aorta and the descending aorta was used in 4 patients. Results: Six postoperative major complications occurred in 5 patients, including postoperative bleeding (n = 3), intraoperative bleeding (n = 1), chylothorax (n = 1), and respiratory failure (n = 1). The postoperative morbidity rate was 31%, and the mortality rate was 12.5% (2/16). Furthermore, 4 patients died of systemic tumor relapse, and 1 patient died of intrapleural recurrence. Nine patients were alive after a median follow-up of 54 months (range, 12-199 months). The median survival time of patients with postoperative pathologic N0 disease was 31 months, whereas it was 10 months for those with pathologic N2 or N3 disease. Five-year survivals were 70% for patients with N0 disease and 16.7% for patients with N2 or N3 disease (P = .0070). Conclusions: Although pulmonary resection with the involved aorta might cause high surgical morbidity and mortality rates, encouraging long-term survivals were obtained in patients without mediastinal nodal involvement.

Original languageEnglish
Pages (from-to)804-808
Number of pages5
JournalJournal of Thoracic and Cardiovascular Surgery
Volume129
Issue number4
DOIs
Publication statusPublished - Apr 2005

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Surgical resection for lung cancer with infiltration of the thoracic aorta'. Together they form a unique fingerprint.

  • Cite this

    Ohta, M., Hirabayasi, H., Shiono, H., Minami, M., Maeda, H., Takano, H., Miyoshi, S., & Matsuda, H. (2005). Surgical resection for lung cancer with infiltration of the thoracic aorta. Journal of Thoracic and Cardiovascular Surgery, 129(4), 804-808. https://doi.org/10.1016/j.jtcvs.2004.05.010