Surgical resection for lung cancer with infiltration of the thoracic aorta

Mitsunori Ohta, Hirohisa Hirabayasi, Hiroyuki Shiono, Masato Minami, Hajime Maeda, Hiroshi Takano, Shinichiro Miyoshi, Hikaru Matsuda

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Objective: The purpose of this study was to evaluate the results of a combined resection of the thoracic aorta and primary lung cancer. Methods: Sixteen patients underwent thoracic aorta resection along with a left pneumonectomy (n = 6), left upper lobectomy (n = 9), or partial lung resection (n = 1), of whom 10 also received preoperative induction therapy. Cardiopulmonary bypass was used in 10 patients, and a passive shunt between the ascending aorta and the descending aorta was used in 4 patients. Results: Six postoperative major complications occurred in 5 patients, including postoperative bleeding (n = 3), intraoperative bleeding (n = 1), chylothorax (n = 1), and respiratory failure (n = 1). The postoperative morbidity rate was 31%, and the mortality rate was 12.5% (2/16). Furthermore, 4 patients died of systemic tumor relapse, and 1 patient died of intrapleural recurrence. Nine patients were alive after a median follow-up of 54 months (range, 12-199 months). The median survival time of patients with postoperative pathologic N0 disease was 31 months, whereas it was 10 months for those with pathologic N2 or N3 disease. Five-year survivals were 70% for patients with N0 disease and 16.7% for patients with N2 or N3 disease (P = .0070). Conclusions: Although pulmonary resection with the involved aorta might cause high surgical morbidity and mortality rates, encouraging long-term survivals were obtained in patients without mediastinal nodal involvement.

Original languageEnglish
Pages (from-to)804-808
Number of pages5
JournalJournal of Thoracic and Cardiovascular Surgery
Volume129
Issue number4
DOIs
Publication statusPublished - Apr 2005
Externally publishedYes

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Thoracic Aorta
Lung Neoplasms
Survival
Aorta
Hemorrhage
Morbidity
Chylothorax
Recurrence
Lung
Pneumonectomy
Mortality
Cardiopulmonary Bypass
Respiratory Insufficiency

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Ohta, M., Hirabayasi, H., Shiono, H., Minami, M., Maeda, H., Takano, H., ... Matsuda, H. (2005). Surgical resection for lung cancer with infiltration of the thoracic aorta. Journal of Thoracic and Cardiovascular Surgery, 129(4), 804-808. https://doi.org/10.1016/j.jtcvs.2004.05.010

Surgical resection for lung cancer with infiltration of the thoracic aorta. / Ohta, Mitsunori; Hirabayasi, Hirohisa; Shiono, Hiroyuki; Minami, Masato; Maeda, Hajime; Takano, Hiroshi; Miyoshi, Shinichiro; Matsuda, Hikaru.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 129, No. 4, 04.2005, p. 804-808.

Research output: Contribution to journalArticle

Ohta, M, Hirabayasi, H, Shiono, H, Minami, M, Maeda, H, Takano, H, Miyoshi, S & Matsuda, H 2005, 'Surgical resection for lung cancer with infiltration of the thoracic aorta', Journal of Thoracic and Cardiovascular Surgery, vol. 129, no. 4, pp. 804-808. https://doi.org/10.1016/j.jtcvs.2004.05.010
Ohta, Mitsunori ; Hirabayasi, Hirohisa ; Shiono, Hiroyuki ; Minami, Masato ; Maeda, Hajime ; Takano, Hiroshi ; Miyoshi, Shinichiro ; Matsuda, Hikaru. / Surgical resection for lung cancer with infiltration of the thoracic aorta. In: Journal of Thoracic and Cardiovascular Surgery. 2005 ; Vol. 129, No. 4. pp. 804-808.
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