Sulbactam·ampicillin in urinary tract infections

Daisuke Yamada, Yositsugu Nasu, Masaya Tsugawa, Mikio Kishi, Hiromi Kumon, Hiroyuki Ohmori, Katsuichi Nanba, Yasuhiro Katayama, Nobuyuki Akazawa, Toshihiko Asahi

Research output: Contribution to journalArticle

Abstract

We clinically investigated a new combination drug, sulbactam·ampicillin (SBT·ABPC) at the ratio 1:2, in the urological field. SBT·ABPC was administered to 24 patients with complicated urinary tract infections at a dose of 1.5 g twice daily for 5 days. The clinical efficacy rate was 75% according to the criteria of the Japanese UTI committee. Bacteriologically, 23 of 29 organisms (79%) were eradicated. There were no subjective side effects, but slight elevation of transaminase was noted in three cases.

Original languageEnglish
Pages (from-to)415-423
Number of pages9
JournalCHEMOTHERAPY
Volume36
DOIs
Publication statusPublished - Jan 1 1988

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Infectious Diseases
  • Pharmacology
  • Drug Discovery
  • Oncology

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  • Cite this

    Yamada, D., Nasu, Y., Tsugawa, M., Kishi, M., Kumon, H., Ohmori, H., Nanba, K., Katayama, Y., Akazawa, N., & Asahi, T. (1988). Sulbactam·ampicillin in urinary tract infections. CHEMOTHERAPY, 36, 415-423. https://doi.org/10.11250/chemotherapy1953.36.Supplement8_415